肠道微生物群与慢性病毒性肝炎的关系

Relationship Between Intestinal Microflora and Chronic Viral Hepatitis

肠道微生物群参与多种疾病的调控,肠-肝轴理论提出为肠道微生物群和肝脏疾病的关系提供的新的思路。乙、丙、丁型病毒性肝炎多呈慢性感染,长期未予控制,可发展为肝硬化、肝癌等。因此,研究肠道微生物群与慢性病毒性肝炎之间的关系具有重要意义。目前研究多集中于对乙型、丙型病毒肝炎,本文现对慢性乙型、丙型病毒性肝炎与肠道微生物群的关系进行综述,以期为指导疾病的防治,改善患者的生存预后提供参考。

Intestinal microflora has been proved to be involved in the regulation of many diseases.The gut-liver axis theory provides a new idea for the relationship between gut microbiota and liver diseases.Hepatitis B,C,D are chronic infected,and long-term uncontrolled,which will finally be malignantly transformed into cirrhosis,liver cancer.Therefore,it is of great significance to study the relationship between intestinal microflora and chronic viral hepatitis.At present,most studies focus on viral hepatitis B and C.This paper reviews the relationship between chronic viral hepatitis B and C and intestinal microflora,in order to guide the prevention and treatment of diseases and improve the prognosis of patients.