新型冠状病毒肺炎流行期间广州市HIV感染者的心理状态

Mental health status among people living with HIV in Guangzhou during the COVID-19 outbreak

目的了解HIV感染者在新型冠状病毒肺炎(COVID-19)流行期间的心理健康状态及其影响因素。方法采用医院焦虑抑郁量表(HADS)对广州市550名HIV感染者进行测评,采用Logistic回归模型分析焦虑或抑郁的影响因素。结果在515份(93.6%)有效问卷中,焦虑或抑郁发生率占32.8%,焦虑发生率为21.7%,抑郁发生率为23.3%。服用二线药物(OR=2.043,95%CI:1.191~3.504)、自费药物(OR=6.711,95%CI:1.580~28.643)、防疫物资储备不充足(OR=2.820,95%CI:1.775~4.500)、服药依从性差(OR=3.145,95%CI:1.621~6.160)是HIV感染者焦虑或抑郁的危险因素;本科及以上学历(OR=0.567,95%CI:0.336~0.937)、积极应对(OR=0.882,95%CI:0.852~0.911)是HIV感染者焦虑或抑郁的保护因素。结论在COVID-19流行期间,HIV感染者的焦虑或抑郁发生率较高,影响因素多样,提高服药依从性、加强防疫物资储备及促进积极应对可能会降低HIV感染者的焦虑或抑郁。

Objective To investigate the mental health status and associated factors among people living with HIV(PLWH)in Guangzhou during the coronavirus disease(COVID-19)outbreak.Methods A total of 550 PLWH were recruited from Guangzhou.Anxiety and depressive symptoms were assessed by the Hospital Anxiety and Depression Scale(HADS).Logistic regression models were employed to identify factors associated with anxiety or depressive symptoms.Results Out of 550 questionnaires collected,515(93.6%)were valid.Almost one-third(32.8%,169/515)of PLWH experienced anxiety or depressive symptoms.Specifically,21.7%of the participants experienced anxiety,and 23.3%experienced depressive symptoms.Using second-line drugs(OR=2.043,95%CI:1.191~3.504),self-funded drugs(OR=6.711,95%CI:1.580~28.643),insufficient supplies for preventive measures against COVID-19 infection(OR=2.820,95%CI:1.775~4.500),poor medicine adherence(OR=3.145,95%CI:1.621~6.160)were risk factors of anxiety or depressive symptoms.In contrast,bachelor’s degree or above(OR=0.567,95%CI:0.336~0.937)and positive coping(OR=0.882,95%CI:0.852~0.911)were protective factors.Conclusions PLWH were at high risk of anxiety or depression during the COVID-19 outbreak,and the associated factors were diverse.The prevalence e of anxiety or depression among PLWH might be reduced by enhancing medicine adherence,strengthening the storage of anti-epidemic materials,and taking positive coping approaches.