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罗哌卡因复合右美托咪定用于肱骨骨折手术中的麻醉效果

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摘要 目的观察罗哌卡因复合右美托咪定用于肱骨骨折手术患者中的麻醉效果。方法选取2017年6月-2020年6月江西省大余县人民医院麻醉科对肱骨骨折手术患者60例予臂丛神经阻滞,按双盲法随机分为观察组和对照组,各30例。对照组使用罗哌卡因麻醉,观察组使用罗哌卡因复合右美托咪定麻醉。比较2组神经阻滞情况、镇痛持续时间、苏醒质量[采用警觉—镇静评分(OAAS)评估],不同时间点生命体征指标[心率(HR)、平均动脉压(MAP)、收缩压(SBP)、舒张压(DBP)]差异。结果观察组感觉神经阻滞及运动神经阻滞起效时间均短于对照组,但持续时间、镇痛持续时间均长于对照组(P<0.01)。拔管3 h后,观察组的OAAS评分高于对照组(P均<0.01);插管前(T_(0))、手术30 min时(T_(3))、手术完毕时(T_(4)),2组HR、MAP、SBP、DBP比较差异无统计学意义(P>0.05);手术开始时(T_(1))、手术10 min时(T_(2)),观察组HR、MAP、SBP、DBP优于对照组(P均<0.01)。结论罗哌卡因复合右美托咪定用于肱骨骨折手术麻醉效果显著,可延长镇痛持续时间,改善患者苏醒质量,稳定患者生命体征,值得临床推广应用。
出处 《临床合理用药杂志》 2022年第5期87-89,共3页 Chinese Journal of Clinical Rational Drug Use
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  • 1涂冬霞.小剂量罗哌卡因腰-硬联合麻醉用于老年患者骨科手术的临床观察[J].医学信息(医学与计算机应用),2014,0(3):90-90. 被引量:1
  • 2GRAF B M, ABRAHAM I, EBERBACH N, et al. Differences in eardiotoxicity of bupivaeaine and ropivaeaine are the result of physieoehemieal and stereoselective propertiesEJ]. Anesthesiology, 2002, 96(6): 1427-1434.
  • 3SINGELYN F J, GOUVERNEUR J M, ROBERT A. A minimum dose of clonidine added to mepivaeaine prolongs the duration of anesthesia and analgesia after axillary brachial plexus blockEJ]. Anesth Analg, 1996, 83(5): 1046-1050.
  • 4SINGELYN F J, DANGOISSE M, BARTHOLOMI~E S, et al. Adding clonidine to mepivaeaine prolongs the duration of anesthesia and analgesia after axillary brachial plexus block [J]. Reg Anesth, 1992, 17(3): 148-150.
  • 5DUMA A, URBANEK B, SITZWOHL C, et al. Clon[d[ne as an adjuvant to local anaesthetic axillary brachial plexus block: a randomized, controlled studyEJ']. Br J Anaesth, 2005, 94(1): 112-116.
  • 6KANAZI G E, AOUAD M T, JABBOUR-KHOURY S I, et al. Effect of low-dose dexmedetomidine or clonidine on the characteristics of bupivacaine spinal block [ J ]. Acta Anaesthesiol Stand, 2006, 50(2): 222-227.
  • 7MEMI~D, TURAN A, KARAMANLIO(~LU B, et al. Adding dexmedetomidine to lidocaine for intravenous regional anesthesia[J]. Anesth Analg, 2004, 98(3)~ 835- 840.
  • 8ESMAOGLU A, MIZRAK A, AKIN A, et al. Addition of dexmedetomidine to lidocaine for intravenous regional anaesthesia[J]. EurJ Anaesthesiol, 2005, 22(6): 447-451.
  • 9SWAMI S S, KENIYA V M, LADI S D, et al. Comparison of dexmedetomidine and clonidine (32 agonist drugs) as an adjuvant to local anaesthesia in supraclavicular brachial plexus block.. A randomised double-blind prospective study EJ]. Indian J Anaesth, 2012, 56(3)~ 243-249.
  • 10BRUMMETT C M, NORAT M A, PALMISANO J M, et al. PerineuraF administration of dexmedetQmidirte in eomhit~ation with bupivacaine enhances sensory and motor blockade in sciatic nerve block without inducing neurotoxicity in rat [ J ]. Anesthesiology, 2008, 109(3) .. 502-511.

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