宫腔镜下子宫内膜息肉切除术对术后辅助生殖妊娠结局的影响

Influence of hysteroscopic endometrial polypectomy for treating women on their pregnancy outcomes by IVF-ET after operation

目的:探讨宫腔镜下子宫内膜息肉切除术(TCRP)对患者术后行体外受精-胚胎移植(IVF-ET)妊娠结局的影响。方法:回顾性分析本院2018年3月-2020年5月收治的82例接受IVF-ET的子宫内膜息肉不孕患者临床资料,按照治疗方式不同分组各41例,刮宫组采用宫腔镜刮宫术治疗,TCRP组采用TCRP术治疗。观察两组子宫内膜血流信号分型及血流参数,比较两组IVF-ET妊娠结局。结果:行IVF-ET胚胎移植日,子宫内膜血流信号a型率两组均高于术前且TCRP组高于刮宫组,阻力指数(RI)、搏动指数(PI)两组均低于术前且TCRP组低于刮宫组,临床妊娠率TCRP组(58.5%)高于刮宫组(34.2%)(均P<0.05),生化妊娠率TCRP组(2.4%)与刮宫组(7.3%)无差异(P>0.05)。结论:TCRP术能够改善子宫内膜患者的子宫内膜容受性血流指标,利于患者术后行IVF-ET妊娠结局。

Objective:To explore the influence of hysteroscopic endometrial polypectomy(TCRP)for treating women on their pregnancy outcomes by in vitro fertilization-embryo transfer(IVF-ET)after operation.Methods:The clinical data of 82 infertile patients with endometrial polyps who had received IVF-ET were analyzed retrospectively.There women were divided into control group and study group(41 cases in each group)according to different treatment methods.The women in the study group were treated with TCRP and the women in the control group were treated with hysteroscopic curettage.The classification and parameters of endometrial blood flow signal of the women in the two groups were observed.And the pregnancy outcomes of the women were compared between the two groups.Results:The rate of type a of endometrial blood flow signal on the embryo transfer day of the women in both groups in IVF-ET was significantly higher than that before operation,and which of the women in the study group was significantly higher than that of the women in the control group.The values of resistance index(RI)and pulsation index(PI)of the women in both groups were significantly lower than those before operation,and which of the women in the study group were significantly lower than those of the women in the control group.The clinical pregnancy rate of the women(58.5%)in the study group was significantly higher than that(34.2%)of the women in the control group(all P<0.05).There was no significant difference in the biochemical pregnancy rate(2.4%vs.7.3%)of the women between the two groups(P>0.05).Conclusion:TCRP can improve endometrial receptivity of the patients with endometrial polyps,and which is beneficial to improve the pregnancy outcomes of patients with endometrial polyps in IVF-ET.