5-氨基酮戊酸光动力联合多功能电离子预处理治疗顽固性跖疣7例临床观察并文献复习

Efficacy of multi-functional electric ion pretreatment combined with 5-aminolevulinic acid photodynamic therapy for 7 cases of refractory plantar warts and literature review

目的观察5-氨基酮戊酸光动力联合多功能电离子预处理治疗顽固性跖疣的临床疗效。方法对2020年7月至2021年8月就诊于滨州医学院附属医院的7例患者采取多功能电离子预处理后联合5-氨基酮戊酸光动力治疗,患者男5例、女2例,年龄11~70岁。经3~6次治疗后,随访3个月观察疗效。结果7例患者经3~6次治疗后皮损完全脱落,皮纹重建,随访3个月未见复发。结论临床上对于皮损较为广泛、常规治疗方法效果不佳的跖疣患者,有效预处理清除疣体联合5-氨基酮戊酸光动力疗法是值得推荐的治疗手段。

Objective To observe the clinical efficacy of multi-functional electric ion pretreatment combined with 5-aminolevulinic acid photodynamic therapy in the treatment of refractory plantar warts.Methods From July 2020 to August 2021,7 cases of refractory plantar warts in Binzhou Medical University Hospital were treated by multi-functional electric ion pretreatment in combination with 5-aminolevulinic acid photodynamic therapy for 3 to 6 times,including 5 males and 2 females,aged 11-70 years.The clinical effect was evaluated after 3 months of follow-up.Results All the plantar warts in the 7 patients were removed completely with dermatoglyph reconstruction after 3-6 times of treatment and no recurrence during the 3-month follow-up visit.Conclusion Effective pretreatment combined with 5-aminolevulinic acid photodynamic therapy is a recommended treatment for patients with refractory plantar warts and poor effect of conventional treatment.