摘要
创面愈合的时间、创缘张力、成纤维细胞增殖和细胞外基质的沉积是瘢痕形成的重要原因,而A型肉毒毒素可在以上多个方面进行调控。A型肉毒毒素应用于瘢痕防治是近年来临床研究的热点之一。该文就国内外学者对A型肉毒毒素在瘢痕防治中的作用机制、临床应用及应用中产生的并发症和不良反应的相关研究进行简要综述。
The wound healing time,tension of wound edge,proliferation of fibroblast,and extracellular matrix deposition are the important factors of scar formation,and botulinum toxin type A can regulate the above.Prevention and treatment of scar with botulinum toxin type A is one of the hot topics of clinical research in recent years.This paper briefly reviews researches by scholars at home and abroad on the mechanism,clinical application,complications,and adverse effects of botulinum toxin type A in scar prevention and treatment.
作者
余震
任盼
张晗
陈辉
马富鑫
Yu Zhen;Ren Pan;Zhang Han;Chen Hui;Ma Fuxin(The Plastic and Reconstructive Surgery Department of Xi'an People's Hospital(Xi'an Fourth Hospital),Xi'an 710004,China;Department of Burns and Plastic Surgery,the Second Affiliated Hospital of Air Force Medical University,Xi'an 710038,China)
出处
《中华烧伤与创面修复杂志》
CAS
CSCD
北大核心
2022年第4期385-388,共4页
Chinese Journal of Burns And Wounds
基金
国家自然科学基金青年科学基金项目(81901980)
陕西省重点研发计划(2021SF-107)。
