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左室功能异常二尖瓣反流病人MRI影像学参数与肌脂蛋白的相关性分析 被引量:2

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摘要 目的分析左室功能异常二尖瓣反流病人MRI影像学参数与肌脂蛋白(SLN)的相关性。方法选取2016年1月—2019年2月秦皇岛市第三医院诊治的50例二尖瓣反流病人为研究组,另选取13名健康人为对照组,对50例二尖瓣反流病人进行MRI影像检查,测量左室功能及容积,并进行连续心室短轴总和测量,对照组相关数据由第三方实验中心提供。采用免疫印迹法及免疫荧光染色检测SLN蛋白表达。结果研究组左室舒张末期内径和左室收缩期末期内径大于对照组(P<0.05),研究组左室质量指数高于对照组(P<0.05)。二尖瓣反流病人心脏显示左室扩张和心室壁变薄。研究组SLN蛋白染色信号强度高于对照组,且与影像学参数存在相关性。结论SLN作为心房调节因子在左室功能异常二尖瓣反流病人中显著上调,且与影像学参数具有相关性。
出处 《中西医结合心脑血管病杂志》 2022年第12期2253-2256,共4页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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