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老年高血压性脑出血患者收缩压与不良预后的相关性研究 被引量:6

Correlation between systolic blood pressure and poor prognosis in elderly patients with hypertensive cerebral hemorrhage
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摘要 目的 探讨老年高血压性脑出血患者收缩压与不良预后的相关性。方法 选择2016年1月至2019年1月收治的老年高血压性脑出血患者67例,记录患者的基本资料,入院时行24 h动态血压,测定收缩压均数、标准差(standard deviation,SD)、变异系数(coefficient of variation,CV)、加权标准差(weighted standard deviation,WSD)、极差等,发病2周时记录美国国立卫生院神经功能缺损评分(national Institutes of health neurological deficit score,NIHSS),发病3个月时记录MRS(modified rankin scale,MRS)量表和BI(barthel index,BI)评分,分析患者各个收缩压指标与不良预后的相关性。结果 平均年龄和颅内血肿量比较,NIHSS轻度组、中度组、重度组依次上升,差异有统计学意义(P<0.05)。收缩压均数、SD、CV、WSD、极差比较,NIHSS轻度组、中度组、重度组依次上升,差异有统计学意义(P<0.05)。预后不良组平均年龄、颅内血肿量及2型糖尿病病史、高脂血症史均高于预后良好组(P<0.05)。预后良好组在收缩压均数、SD、CV、WSD、极差上均低于预后不良组(P<0.05)。Pearson分析显示,患者收缩压均数、SD、CV、WSD、极差与NIHSS评分、mRS评分呈正相关,与BI评分呈负相关(P<0.05)。结论 老年高血压性脑出血患者收缩压各项指标与近远期预后、生活质量密切相关,收缩压越高,近远期预后越差,生活质量越低。 Objective To investigate the correlation between systolic blood pressure and poor prognosis in elderly patients with hypertensive cerebral hemorrhage.Methods A total of 67 elderly patients with hypertensive cerebral hemorrhage who were treated in our hospital from January 2016 to January 2019 were enrolled in the study.The basic information,systolic pressure(SBP)mean,standard deviation(SD),coefficient of variation(CV),weighted standard deviation(WSD)and range were measured,The National Institutes of health neurological deficit score(NIHSS)was performed at the second week of onset,and the Mrs(modified Rankin scale,MRS)and BI(Barthel index,BI)scores were perfomed to analyze the correlation between systolic blood pressure and poor prognosis was analyzed.Results The mean age and the amount of intracranial hematoma were significantly increased in order of NIHSS mild group,moderate group and severe group(P<0.05).And the mean systolic blood pressure,SD,CV,WSD,range were significantly increased in order of NIHSS mild group,moderate group and severe group(P<0.05).Moreover the average age,the amount of intracranial hematoma,the history of type 2 diabetes mellitus and hyperlipidemia in poor prognosis group were significantly higher than those in good prognosis group(P<0.05),and the mean systolic blood pressure,SD,CV,WSD and range in good prognosis group were significantly lower than those in poor prognosis group(P<0.05).Pearson analysis showed that mean systolic blood pressure,SD,CV,WSD and range were positively correlated with NIHSS score and MRS score,however,which were negatively correlated with BI score(P<0.05).Conclusion The systolic blood pressure related indexes in elderly patients with hypertensive cerebral hemorrhage are closely related to the short-term and long-term prognosis and life quality of patients.The higher the systolic blood pressure,the worse the short-term and long-term prognosis,the poorer the life quality of patients.
作者 黄国琴 汤维力 贾丽娟 冷亮 HUANG Guoqin;TANG Weili;JIA Lijuan(Department of Neurosurgery,Liyang People’s Hospital,Jiangsu,Liyang 213300,China)
出处 《河北医药》 CAS 2022年第13期1985-1988,共4页 Hebei Medical Journal
关键词 老年人 高血压性脑出血 收缩压 不良预后 the elderly hypertensive cerebral hemorrhage systolic blood pressure poor prognosis
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