液基薄层细胞学检查在宫颈病变病理诊断中的应用效果研究

Application of liquid based thin layer cytology in pathological diagnosis of cervical lesions

目的 探讨采取液基薄层细胞学(TCT)检查对诊断宫颈癌病变病理情况的应用价值。方法 回顾性分析2019年1月~2021年6月接受宫颈病变检查的50例患者临床资料,所有的患者均是采取TCT检查与细胞学检查,以细胞学检查结果为金标准,评价采取TCT检查对宫颈病变病理诊断符合情况。结果 50例患者经TCT检查,同金标准比较鳞状细胞癌(SCC)的符合率为100.00%、高度鳞状上皮内病变(HSIL)的符合率为85.71%、低度鳞状上皮内病变(LSIL)的符合率为77.78%、非典型性鳞状细胞不处外高级别鳞状上皮内病变(ASC-H)的符合率为60.00%、非典型鳞状细胞性质未定(ASCUS)的符合率为88.89%。不同年龄组宫颈病变存在差异,主要是随着年龄增加,CINⅡ和CINⅢ、SCC的例数也增加。结论 应用TCT检查对宫颈病变筛查的价值突出,有助于宫颈癌的早期检出,为疾病尽早干预提供帮助。

Objective To explore the application value of liquid based thin layer cytology(TCT) in the diagnosis of pathological changes of cervical cancer. Methods the clinical data of 50 patients who underwent cervical lesion examination from january2019 to June 2021 were retrospectively analyzed. All patients were examined by TCT and cytology. The cytology Results were taken as the gold standard to evaluate the coincidence of TCT in the pathological diagnosis of cervical lesions. Results compared with the gold standard, the coincidence rate of squamous cell carcinoma(SCC), high-grade squamous intraepithelial lesion(HSIL)and low-grade squamous intraepithelial lesion(LSIL) was 100.00%, 85.71%, 77.78%, 60.00% and 88.89% respectively in 50 patients with atypical squamous cell carcinoma and high-grade squamous intraepithelial lesion(ASC-H). There are differences in cervical lesions in different age groups. The main reason is that with the increase of age, the number of cases of CIN Ⅱ, CIN Ⅲ and SCC also increases. Conclusion TCT is of great value in screening cervical lesions, which is helpful for early detection of cervical cancer and early intervention.