康妇消炎栓联合左氧氟沙星治疗慢性盆腔炎所致疼痛的临床研究

Effect of Kangfu Xiaoyan Suppository Combined with Levofloxacin on Pain Caused by Chronic Pelvic Inflammatory Disease

目的:探究康妇消炎栓联合左氧氟沙星对慢性盆腔炎所致疼痛的治疗效果。方法:选取2019年1月至2021年1月德驭医疗马鞍山总医院收治的慢性盆腔炎患者80例作为研究对象,按照治疗方法不同分为对照组和观察组,每组40例,对照组采用左氧氟沙星治疗,观察组采用康妇消炎栓配合左氧氟沙星治疗,比较2组患者临床疗效,炎症介质水平(白细胞介素-6、白细胞计数、C反应蛋白),临床症状改善时间,视觉模拟评分法(VAS)、包块直径、盆腔积液深度,以及不良反应。结果:观察组临床疗效为95.00%,明显高于对照组的75.00%(P<0.05)。治疗后,观察组患者的白细胞介素-6、白细胞计数、C反应蛋白水平明显低于对照组(均P<0.05)。治疗后,观察组症状改善时间明显优于对照组(P<0.05);治疗后,观察组患者的VAS评分、包块直径、盆腔积液深度明显低于对照组(均P<0.05);观察组不良反应总发生率为10.00%,低于对照组的27.5%(P<0.05)。结论:康妇消炎栓配合左氧氟沙星治疗慢性盆腔炎疗效较好,能够帮助患者控制病情,降低炎症反应,值得临床推广。

Objective:To explore the effect of Kangfu Xiaoyan suppository combined with levofloxacin on pain caused by chronic pelvic inflammatory disease.Methods:A total of 80 patients who were diagnosed with chronic pelvic inflammatory disease in Maanshan General Hospital of Ronger-Duree Healthcare,Maanshan City,Anhui Province from January 2019 to January 2021 were selected and divided into a control group(40 cases)and an observation group(40 cases)according to treatment method.The control group was treated with levofloxacin,while the observation group was treated with Kangfu Xiaoyan Suppository combined with levofloxacin.The clinical effect,and inflammatory factors(interleukin-6,white blood cell count,C-reactive protein),improvement time of clinical symptoms,visual analogue scale(VAS),mass diameter,depth of pelvic effusion,and adverse reactions of the two groups were compared.Results:The clinical effective rate of the observation group was 95.00%higher than 75.00%of the control group(P<0.05).After treatment,the interleukin-6 level,white blood cell count and C-reactive protein level in the observation group were lower than those in the control group(P<0.05),and the improvement time of clinical symptoms in the observation group was better than that in the control group(P<0.05).Compared with the conditions in the control group,the VAS score,mass diameter and depth of pelvic effusion in the observation group were decreased(all P<0.05).In terms of adverse reactions,the control group(27.5%)was higher than the observation group(10.00%,P<0.05).Conclusion:Kangfu Xiaoyan Suppository combined with levofloxacin was effective in the treatment of chronic pelvic inflammatory disease,which helped patients control the disease and reduced inflammatory reaction,and was worthy of clinical promotion.