猪妊娠期母胎对话的研究进展

A Review of Mother-fetal Dialogue during Pregnancy in Sows

母胎对话是母体与胎儿在妊娠过程中建立的一种复杂对话关系,是成功附植和妊娠的必要条件,这一对话关系受到众多因素的调控。母胎对话异常会导致胚胎附植及妊娠的失败,并影响妊娠期胎儿的正常发育,因此妊娠期的母胎对话对于提高繁殖效率意义重大。本文主要以猪为模式动物综述了母体与胎儿从妊娠识别(妊娠前)、胚胎附植(妊娠中)到胎儿发育(妊娠后)过程中影响母胎对话的因素,包括激素、细胞因子、黏附因子、基因和蛋白质等,以期为猪母胎对话的研究和产仔数提高提供参考。

Maternal-fetal dialogue is a complex dialogue between mother and fetus during pregnancy, which is a necessary process for successful implantation and pregnancy and is regulated by many factors. Abnormal mother-fetus dialogue can lead to the failure of embryo implantation and pregnancy, and can affect the normal development of fetus during pregnancy. Therefore, mother-fetus dialogue during pregnancy is of great significance for improving the litter size and reproductive efficiency of pigs. The review summarized the factors influencing the mother-fetus dialogue from pregnancy recognition(before pregnancy), embryo implantation(pregnancy) to fetal development(after pregnancy) using sows as a model, including hormones, cytokines, adhesion factors, genes and proteins, etc, which can provide reference for pig maternal-fetal dialogue study and increasing litter size in pig industry.