血清胆红素与尿酸对冠心病患者的临床诊断的价值

Value of Serum Bilirubin and Uric Acid in Clinical Diagnosis of Patients with Coronary Heart Disease

目的:探讨血清胆红素和尿酸检验对冠心病患者诊断价值。方法:选取2020年10月-2021年9月东莞市凤岗医院收治的冠心病患者100例为观察组,选取同期健康体检者100例为对照组,检验并比较两组患者血清胆红素水平和尿酸水平,以及不同程度冠状动脉狭窄患者的血清胆红素和尿酸水平。结果:观察组直接胆红素、间接胆红素、总胆红素水平低于对照组,尿酸水平高于对照组,差异有统计学意义(P<0.001);Gensini积分>40分患者直接胆红素、间接胆红素、总胆红素水平更低,尿酸水平更高,差异有统计学意义(P<0.001)。结论:血清胆红素和尿酸可在冠心病临床检验中产生良好诊断效果,与健康体检者相比,冠心病患者的血清胆红素水平更低,尿酸水平更高,对疾病严重程度的评估具有较高的参考价值。

Objective:To explore the diagnostic value of serum bilirubin and uric acid test in patients with coronary heart disease.Methods:100 patients with coronary heart disease admitted to Dongguan Fenggang Hospital from October 2020 to September 2021 were selected as the observation group,and 100 healthy subjects during the same period were selected as the control group.The serum bilirubin and uric acid levels of the two groups and those of patients with different degrees of coronary artery stenosis were tested and compared.Results:The levels of direct bilirubin,indirect bilirubin and total bilirubin in the observation group were lower than those in the control group,and the level of uric acid was higher than that in the control group,with statistical significance(P<0.001).The level of direct bilirubin,indirect bilirubin and total bilirubin was lower in patients with Gensini score>40,and the level of uric acid was higher,the difference was statistically significant(P<0.001).Conclusion:Serum bilirubin and uric acid can produce a good diagnostic effect in clinical examination of coronary heart disease.Compared with healthy subjects,serum bilirubin and uric acid levels are lower in patients with coronary heart disease,which has a high reference value for the assessment of disease severity.