化瘀通络汤治疗短暂性脑缺血发作临床观察

Clinical Observation on Huayu Tongluo Decoction in Treating Transient Ischemic Attack

目的探讨并分析总结化瘀通络汤治疗短暂性脑缺血发作的临床效果。方法将98例短暂性脑缺血发作的患者随机分为研究组49例、对照组49例,对照组给予改善脑血流、活化脑细胞、抗血小板聚集等西医基础治疗,研究组在对照组基础上加用化瘀通络汤,2组患者均治疗2周。对比2组患者治疗后临床疗效、治疗2周及治疗后4周短暂性脑缺血发作次数、治疗前后中医证候积分。结果在临床疗效方面,研究组总有效率为95.92%(47/49),对照组总有效率为73.47%(36/49),治疗组疗效优于对照组(P<0.05);在短暂性脑缺血发作次数方面比较,研究组治疗2周与治疗后4周均明显优于对照组(P<0.01);在中医证候积分方面比较,研究组优于对照组(P<0.05)。结论化瘀通络汤能显著改善短暂性脑缺血发作患者的临床症状,提高临床治疗效果,改善患者的生活质量,减少短暂性脑缺血发作的发作率及脑卒中发生率,临床经验值得进一步推广。

Objective To explore and summarize the clinical effect of Huayu Tongluo decoction in the treatment of transient ischemic attack.Methods 98 patients with transient ischemic attack were randomly divided into study group of 49 cases and control group of 49 cases.The control group was given Western medicine basic treatment such as improving cerebral blood flow,activating brain cells and anti-platelet aggregation,while the study group was given Huayu Tongluo decoction on the basis of the control group.Both groups were treated for 2 weeks.The clinical efficacy after treatment,the number of transient ischemic attacks 2 weeks and 4 weeks after treatment,and the traditional Chinese medicine(TCM)syndrome scores before and after treatment were compared between the two groups.Results In terms of clinical efficacy,the total effective rate of the study group was 95.92%(47/49),and the total effective rate of the control group was 73.47%(36/49).The curative effect of the treatment group was better than that of the control group(P<0.05).The number of transient ischemic attacks in the study group was significantly better than that in the control group 2 weeks after treatment and 4 weeks after treatment(P<0.01).The study group was better than the control group in TCM syndrome scores(P<0.05).Conclusion Huayu Tongluo decoction can significantly improve the clinical symptoms of patients with transient ischemic attack,enhance the clinical treatment effect,improve the life quality of patients and reduce the incidence of transient ischemic attack and stroke.The clinical experience is worthy of further promotion.