甘草泻心汤治疗复发性口腔溃疡的理论基础及作用机制探析

Theoretical Basis and Mechanism of Action of Gancao Xiexin Decoction in the Treatment of Recurrent Mouth Ulcers

复发性口腔溃疡是常见的一种口腔黏膜疾病,表现为口腔黏膜的溃疡性病变,病程持久,疼痛剧烈,缠绵难愈,影响患者饮食、情绪,甚者影响患者睡眠及整体生活质量。目前西医方面主要以对症治疗为主,以缓解疼痛、促进溃疡面愈合、降低疾病复发率为主要治疗目的,但远期治疗效果不理想。甘草泻心汤是《伤寒杂病论》所载的经典名方,临床应用治疗复发性口腔溃疡疗效确切,文章旨在通过对甘草泻心汤治疗复发性口腔溃疡理论基础的深入探讨,以期更好的指导临床应用。

Recurrent oral ulcer is a common oral mucosal disease, which is manifested as ulcerative lesions of the oral mucosa. The course of the disease is prolonged, the pain is severe, and it is difficult to heal. It affects the patient’s diet, mood, and even affects the patient’s sleep and overall quality of life. At present, western medicine is mainly based on symptomatic treatment, and the main therapeutic purpose is to relieve pain, promote ulcer surface healing, and reduce disease recurrence rate, but the long-term treatment effect is not ideal. Gancao Xiexin decoction is a classic and famous prescription in Treatise on Febrile Diseases and Miscellaneous Diseases, and its clinical application is effective in treating recurrent oral ulcers. Good guide for clinical application.