破坏性心境失调障碍成因、诊断及干预的研究进展(综述)

Review of studies on the causes,diagnostic criteria and intervention of disruptive mood dysregulation disorder

作为《精神障碍诊断与统计手册(第五版)》(DMS-5)中的新增类别,破坏性心境失调障碍是一种以持续性易激惹和间歇性情绪爆发为特征的儿童和青少年情绪障碍。本文通过梳理国际研究进展,阐述了与此有关的生理学成因、心理学成因与环境致病因素,所采用的易激惹情绪、行为障碍、功能性评定的测量工具,以及药物和心理干预措施。当前研究还较为初步,疾病成因不够明确、诊断标准存在争议、干预措施有限。今后需进一步探明病理机制,关注跨文化环境因素差异,改进诊断标准,构建病征识别的量化标准体系,探索多模态干预措施,为疾病的筛查、诊断、治疗提供理论参考。

Disruptive Mood Dysregulation Disorder(DMDD)is a child and adolescent Mood Disorder characterized by chronic irritability and temper outburst.This article summarizes previous studies on the physiological,psychologicalandenvironmental pathogenic factors of DMDD,reviews the measurement tools for emotional irritability,behavioral disorder as well as functional assessment,investigates its drug and psychological intervention measures.Research finds that despite some results have been achieved,the causes of DMDD remain unclear,diagnostic criteria are controversial,and the intervention measures are limited.Future research should clarify the pathogenesis of DMDD,concentrate on its cross-cultural pathogenic factors differences,improve itsdiagnostic criteria,establish the quantitative indicator system for DMDD symptom recognition and explore the method to combine multiple intervention measures.