异腈参与的光催化反应研究进展

Recent Advances in Photocatalytic Reactions with Isocyanides

异腈是一类有价值的C1结构单元,广泛应用于有机化学、组合化学、生物医药等领域,其衍生物更是构建生物活性分子和复杂的天然产物的有效模块.根据异腈参与光催化反应的机制进行分类,综述了近五年异腈参与光催化反应的研究进展,着重讨论了光催化剂、底物适用性以及反应机制,并对该领域存在的挑战以及未来发展趋势进行了浅谈和展望.

Isocyanides are a class of valuable C1 building blocks,widely used in organic chemistry,combinatorial chemistry,biomedicine and other fields,and their derivatives are effective building blocks for the synthesis of bioactive molecules and complex natural products.Herein,the recent advances in photocatalytic reactions with isocyanides are summarized according to the types of the reaction mechanism.The photocatalyst,substrate range and reaction mechanism are emphatically discussed.Finally,the challenges and future development trends of this research field are discussed and prospected.