后路手术内固定融合术治疗脊柱骨折对脊柱功能的影响

Effects of Posterior Surgical Internal Fixation Fusion on Spinal Function in the Treatment of Spinal Fracture

目的探究后路手术内固定融合术治疗脊柱骨折对脊柱功能的影响。方法选择2020年11月至2022年11月在社旗县人民医院治疗的82例脊柱骨折患者,应用随机数表法将其分为对照组(前路内固定融合术)及观察组(后路手术内固定融合术)各41例,比较两组治疗有效率、伤锥影像学参数、炎症因子、应激指标、功能障碍指数、疼痛评分、并发症发生率。结果观察组治疗有效率高于对照组,差异有统计学意义(P<0.05)。观察组锥体后缘高度、锥体前缘高度高于对照组,且Cobb`s角低于对照组,差异有统计学意义(P<0.05)。观察组肿瘤坏死因子(TNF-α)、C反应蛋白(CRP)、降钙素原(PCT)低于对照组,差异有统计学意义(P<0.05)。观察组促肾上腺皮质激素(ACTH)低于对照组,氧化蛋白产物(AOPP)、谷胱甘肽过氧化物酶(GSH-PX)高于对照组,差异有统计学意义(P<0.05)。观察组功能障碍指数(ODI)低于对照组,视觉模拟量表评分(VAS)低于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论脊柱骨折采用后路内固定融合术治疗,能够减轻应激反应、炎症反应,促进脊柱功能恢复,改善疼痛程度,降低并发症发生率。

Objective To investigate the effect of posterior internal fixation fusion on spinal function in the treatment of spinal fracture.Methods A total of 82 patients with spinal fractures treated in our hospital from November 2020 to November 2022 were selected and divided into a control group(anterior internal fixation fusion)and an observation group(posterior internal fixation fusion)with 41 cases each by random number table method.The effective rate,imaging parameters,inflammatory factors,stress index,dysfunction index,pain score,and complication rate were compared between the two groups.Results The effective rate of treatment in the observation group was higher than that in the control group,the difference was statistically significant(P<0.05).The height of the posterior edge and anterior edge of the cone in the observation group was higher than that in the control group,and Cobb's angle was lower than that in the control group,the difference was statistically significant(P<0.05).Tumor necrosis factor(TNF-α),C-reactive protein(CRP),and procalcitonin(PCT)in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).The adrenocorticotropic hormone(ACTH)in the observation group was lower than that in the control group,and the oxidized protein product(AOPP)and glutathione peroxidase(GSH-PX)in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The dysfunction index(ODI)and visual analog scale(VAS)scores of the observation group were lower than those of the control group,and the differences were statistically significant(P<0.05).The incidence of complications in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion Posterior internal fixation and fusion therapy for spinal fracture can reduce stress and inflammation,promote the recovery of spinal function,improve the degree of pain,and reduce the incidence of complications.