抑郁症患者睡眠障碍发生情况及其影响因素分析

Analysis of the Occurrence of Sleep Disorders and Their Influencing Factors in Depressed Patients

目的:研究抑郁症患者睡眠障碍发生情况并分析其影响因素。方法:选取2020年1月至2022年1月泉州市第三医院收治的抑郁症患者180例作为研究对象,按照匹兹堡睡眠质量指数(PSQI)量表评估结果分为对照组(n=81)和观察组(n=99)。对照组PSQI总分<8分,观察组PSQI总分≥8分。对2组患者一般资料(性别、年龄、抑郁症病程、学历背景、婚姻状态等)、负性情绪[汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)]、社会支持[社会支持评定量表(SSRS)]进行调查评估,使用单因素与多因素分析方法分析抑郁症患者睡眠障碍发生的影响因素。结果:抑郁症患者睡眠障碍的发生率为55.00%;睡眠障碍组与无睡眠障碍组的性别、学历背景比较,差异无统计学意义(P>0.05);睡眠障碍组的年龄、抑郁症病程低于无睡眠障碍组,差异有统计学意义(P<0.05);同时睡眠障碍组的HAMD评分、HAMA评分高于无睡眠障碍组,SSRS评分低于无睡眠障碍组,差异有统计学意义(P<0.05);多因素Logistic回归分析结果提示年龄、抑郁症病程、HAMD评分、HAMA评分、SSRS评分均是抑郁症患者睡眠障碍发生的独立影响因素(P<0.05)。结论:大部分抑郁症患者均会存在睡眠障碍,年龄、抑郁症病程、负性情绪以及社会支持是导致抑郁症患者发生睡眠障碍的独立影响因素。

Objective:To study the occurrence of sleep disorders in depressed patients and analyze the factors influencing them.Methods:A total of 180 patients with depression admitted to the Third Hospital of Quanzhou City from January 2020 to January 2022 were selected as the research objects.According to the evaluation results of the Pittsburgh Sleep Quality Index(PSQI)scale,they were divided into the control group(n=81)and the observation group(n=99).The total PSQI score of the control group is less than 8 points,while the total PSQI score of the observation group is≥8 points.The general data(gender,age,duration of depression,educational background,marital status,etc.),negative emotions[Hamilton Depression Rating Scale(HAMD),Hamilton Anxiety Rating Scale(HAMA)],and social support[Social Support Rating Scale(SSRS)]of the two groups of patients were investigated and evaluated.The single factor and multi factor analysis methods were used to analyze the influencing factors of Sleep disorder in patients with depression.Results:The incidence of sleep disorders in depressed patients was 55.00%;the differences between the sleep disorder group and the no sleep disorder group in terms of gender and educational background were not statistically significant(P>0.05);the age and duration of depression in the sleep disorder group were lower than those in the no sleep disorder group,and the differences were statistically significant(P<0.05);meanwhile,the HAMD score and HAMA score in the sleep disorder group were higher than those in the no sleep disorder group.The SSRS score was lower than the group without sleep disorders The difference was statistically significant(P<0.05);the results of multi-factor logistic regression analysis suggested that age,duration of depression,HAMD score,HAMA score and SSRS score were all independent influencing factors for the occurrence of sleep disorders in depressed patients(P<0.05).Conclusion:Sleep disturbances are present in most depressed patients,and age,duration of depression,negative affect,and social support are all independent influences on the development of sleep disturbances in depressed patients.