排石散联合钬激光碎石术治疗肾结石40例临床观察

Clinical effect of Paishi powder combined with holmium laser lithotripsy in treatment of nephrolithiasis:An analysis of 40 cases

目的:观察壮药排石散联合钬激光碎石术治疗肾结石的临床疗效。方法:将80例肾结石患者随机分成治疗组和对照组,每组各40例。2组均采用钬激光碎石术治疗,术后治疗组给予排石散治疗,对照组给予盐酸坦索罗辛缓释胶囊治疗。比较2组结石有效清除率、结石排出时间、疼痛视觉模拟量表(VAS)评分及血尿、尿路感染、下尿路刺激征等并发症发生情况。结果:结石有效清除率治疗组为95.00%(38/40),对照组为80.00%(32/40),2组比较,差异有统计学意义(P<0.05)。结石排出时间治疗组短于对照组,治疗后2组VAS评分均较治疗前下降,且治疗组低于对照组;术后血尿、尿路感染、下尿路刺激征发生率治疗组均低于对照组,差异均有统计学意义(P<0.05或P<0.01)。结论:排石散联合钬激光碎石术治疗肾结石可显著提高结石清除率,缩短结石排出时间,减轻患者疼痛程度,减少术后并发症的发生,值得临床推广应用。

Objective:To investigate the clinical effect of Zhuang nationality medicine Paishi powder combined with holmium laser lithotripsy in the treatment of nephrolithiasis.Methods:A total of 80 patients with nephrolithiasis were randomly divided into treatment group and control group,with 40 patients in each group.In addition to holmium laser lithotripsy,the patients in the treatment group were given Paishi powder after surgery,and those in the control group were given tamsulosin hydrochloride sustained-release capsules after surgery.The two groups were compared in terms of effective calculus clearance rate,time to calculus expulsion,Visual Analog Scale(VAS)pain score,and complications such as hematuria,urinary tract infection,and lower urinary tract irritation.Results:There was a significant difference in effective calculus clearance rate between the treatment group and the control group[95.00%(38/40)vs 80.00%(32/40),P<0.05].The treatment group had a significantly shorter time to calculus expulsion than the control group,and after treatment,both groups had a significant reduction in VAS score,while the treatment group had a significantly lower score than the control group;compared with the control group,the treatment group had significantly lower incidence rates of hematuria,urinary tract infection,and lower urinary tract irritation after surgery(P<0.05 or P<0.01).Conclusion:In the treatment of nephrolithiasis,Paishi powder combined with holmium laser lithotripsy can significantly improve calculus clearance rate,shorten the time to calculus expulsion,alleviate the degree of pain,and reduce postoperative complications,and therefore,it holds promise for clinical application.