认知行为疗法对围生期女性抑郁症状疗效的Meta分析

A Meta-analysis of the efficacy of cognitive behavioural therapy on depressive symptoms in perinatal women

目的系统评价围生期女性心理体验。方法检索9个电子文献数据库:中国知网(CNKI)、高级(VIP)数字数据库、中国万方数据库、Cochrane图书馆、PubMed、Web of Science、EMbase、PsycINFO、护理学数据库(CINAHL),检索符合条件的随机对照试验(RCT),从建库至2020年11月15日。对符合条件的研究进行筛选、提取,然后由两名研究人员独立评估方法学质量。使用荟萃分析软件(RevMan5.3)进行荟萃分析。遵循系统评价和荟萃分析的首选报告项目清单。结果共纳入13项RCTs,共966名参与者。结果表明,认知行为治疗(CBT)组后可减轻围生期孕妇抑郁症状。同样,在产后(<4个月),结果显示CBT组在改善孕妇抑郁症状方面优于常规护理组。但产后(>4个月)差异无统计学意义。结论认知行为疗法可在短期内有效缓解抑郁症状,但其远期疗效有待进一步临床研究验证。

Objective Systematic evaluation of the quality of the perinatal female psychological experience.Methods Nine electronic literature databases were searched:CNKI(China Knowledge Network),VIP(Very Important Person)digital database,China Wanfang database,the Cochrane library,PubMed,Web of Science,EMbase,PsycINFO,CINAHL(nursing database),and eligible randomised controlled trials(RCT)were retrieved from database establishment to November 15,2020.Eligible studies were screened,extracted,and then independently assessed for methodological quality by two researchers.Meta-analyses were performed using meta-analysis software(RevMan 5.3).Follow the list of preferred reporting items for systematic reviews and meta-analyses.Results A total of 13 RCTs with 966 participants were included.The results showed that depressive symptoms in perinatal pregnant women were reduced after the cognitive behavioural therapy(CBT)group.Likewise,in the postpartum period(<4 months),the results showed that the CBT group was superior to the usual care group in improving maternal depressive symptoms.But postpartum(>4 months)was not statistically different.Conclusion Cognitive behavioral therapy can effectively relieve depressive symptoms in the short term,but its long-term efficacy needs further clinical research to verify.