武汉市交通相关大气污染与艾滋病死亡关系的研究

Study on the Relationship between air pollution and HIV/AIDS death in Wuhan City

目的探索大气污染物(PM_(2.5)、NO_(2)、CO)与武汉市HIV/AIDS患者死亡率的关系。方法收集2017年1月1日到2019年12月31日HIV/AIDS患者死亡数据以及研究期间内的每日平均大气污染物浓度,采用时间分层的病例交叉设计,探索大气污染物浓度和患者死亡率之间的相关性。结果在累计滞后0~4 d内,CO浓度每提高10μg/m^(3),HIV/AIDS患者艾滋病相关死亡率升高1.79%(95%CI:0.04~3.56);PM_(2.5)、NO_(2)浓度变化与HIV/AIDS患者死亡率无统计学关联。结论CO与HIV/AIDS患者艾滋病相关死亡的风险呈正相关,可以为公共卫生部门针对HIV/AIDS患者制定更有效的预防措施提供相关流行病学证据。

Objective To explore the correlation between air pollutants(PM_(2.5),NO_(2),and CO)and the mortality rate of HIV/AIDS patients in Wuhan.Methods The death data of HIV/AIDS patients from 1 January 2017 to 31 December 2019 and the daily average atmospheric pollutant concentration during the study period were collected.A time-stratified case-control study design was used to explore the correlation between atmospheric pollutant concentration and patient mortality.Results For every 10μg/m^(3) increase in CO concentration within 0-4 days of cumulative lag,AIDS-related mortality in HIV/AIDS patients increased by 1.79%(95%CI:0.04-3.56).There was no statistical correlation between PM_(2.5) and NO_(2) concentrations and mortality in HIV/AIDS patients.Conclusion CO is positively correlated with the risk of AIDS-related death in HIV/AIDS patients.This study can provide relevant epidemiological evidence for public health authorities to develop more effective prevention measures for HIV/AIDS patients.