腹腔镜辅助胃癌根治术在胃癌治疗中的应用效果

The application effect of laparoscopic assisted radical gastrectomy in the treatment of gastric cancer

目的以胃癌手术患者作为观察对象,评估腹腔镜辅助胃癌根治术的应用效果。方法选取连云港市东海县中医院2022年9月至2023年8月收治的胃癌住院患者60例,根据手术方式的不同分为对照组和观察组。对照组接受常规胃癌根治术治疗,观察组接受腹腔镜辅助胃癌根治术治疗。比较两组患者手术前后的肾上腺素、皮质醇、促肾上腺皮质激素水平,以及白介素-6、肿瘤坏死因子-α、高敏C反应蛋白水平,并比对两组患者手术情况及术后并发症发生情况。结果术前,两组患者的肾上腺素、皮质醇、促肾上腺皮质激素水平,以及白介素-6、肿瘤坏死因子-α、高敏C反应蛋白水平均较低,且均无显著差异(P>0.05)。术后,两组患者的肾上腺素、皮质醇、促肾上腺皮质激素水平,以及白介素-6、肿瘤坏死因子-α、高敏C反应蛋白水平均有所升高,且对照组显著高于观察组。观察组患者的手术时长、术后首次排气时间均短于对照组,且术中出血量少于对照组,差异均有显著性(P<0.05)。观察组患者术后并发症总发生率为3.33%,显著低于对照组(26.67%),差异均有显著性(P<0.05)。结论腹腔镜辅助胃癌根治术应用于胃癌手术患者时,对患者造成的应激更小,患者术后并发症发生率更低。

Objective To evaluate the application effect of laparoscopic assisted radical gastrectomy in patients undergoing gastric cancer surgery.Method Sixty hospitalized patients with gastric cancer admitted to Donghai County Traditional Chinese Medicine Hospital in Lianyungang City from September 2022 to August 2023 were selected and divided into a control group and an observation group based on different surgical methods.The control group received conventional gastric cancer radical surgery treatment,while the observation group received laparoscopic assisted gastric cancer radical surgery treatment.Compare the levels of adrenaline,cortisol,adrenocorticotropic hormone,as well as interleukin-6 and tumor necrosis factor-αbetween two groups of patients before and after surgery,compare the levels of high sensitivity C-reactive protein surgical situation,and the incidence of postoperative complications between the two groups of patients.Result Prior to surgery,levels of adrenaline,cortisol,adrenocorticotropic hormone,as well as interleukin-6 and tumor necrosis factor-αwere measured in both groups of patients,the levels of high sensitivity C-reactive protein were all low and there was no significant difference(P>0.05).After surgery,the levels of adrenaline,cortisol,adrenocorticotropic hormone,as well as interleukin-6 and tumor necrosis factor-αin both groups of patients,the levels of high sensitivity C-reactive protein were all elevated,and the control group was significantly higher than the observation group.The surgical duration and first postoperative exhaust time of the observation group patients were shorter than those of the control group,and the intraoperative bleeding was less than that of the control group,with significant differences(P<0.05).The total incidence of postoperative complications in the observation group was 3.33%,significantly lower than that in the control group(26.67%),with significant differences(P<0.05).Conclusion Laparoscopic assisted radical gastrectomy is less stressful for patients undergoing gastric cancer surgery and has a lower incidence of postoperative complications.