肥胖和肌量与社区中老年人动脉硬化的关系研究

Study on the relationship between obesity and muscle massand atherosclerosis in middle-aged and elderly people in community

目的:探究肥胖和肌量指标与社区中老年人动脉硬化之间的关系。方法:连续收集蚌埠市东风社区同时完成人体成分分析和动脉硬化检测的1011例中老年人资料。根据臂-踝脉搏波传导速度(baPWV)区分为正常组和硬化组,比较2组身体成分指标、基线资料差异,分析动脉硬化在不同人体成分类型中的发生风险。结果:2组病人年龄、脂肪量(BF)、体脂率(%BF)、四肢骨骼肌质量(ASM)、四肢骨骼肌指数(ASMI)、腰臀比(WHR)、腰围(WC)、baPWV比较,差异均有统计学意义(P<0.01),硬化组中的AMS和AMSI明显低于正常组(P<0.01)。2组间肥胖、肌量及联合分类差异均有统计学意义(P<0.01)。logistic回归分析,肥胖和肌量减少均表现对动脉硬化的风险特征(P<0.05),但在联合分类中肌量对动脉硬化不再表现为风险特征(P>0.05)。结论:中老年人可结合身体成分指标监测动脉硬化发生以及在干预中监测其动态变化,尤其是肥胖、肌量下降和肥胖合并肌量减少者更应该重视动脉硬化的筛查和预防。

Objective:To explore the relationship between obesity and muscle mass index and arteriosclerosis in middle-aged and elderly people in community.Methods:The data of 1011 middle-aged and elderly people who completed both body composition analysis and atherosclerosis testing in Bengbu Dongfeng community were collected consecutively.According to the brachial ankle pulse wave velocity(baPWV),they were divided into normal group and sclerotic group.The difference of body composition indexes and baseline data were compared between the two groups,and the risk of atherosclerosis in different body composition types was analyzed.Results:There were significant differences in age,body fat(BF),body fat rate(%BF),appendicular skeletal muscle mass(ASM),oppendicular skeletal muscle mass index(ASMI),waist hip ratio(WHR),waist circumference(WC),and baPWV of the two groups(P<0.01).The AMS and AMSI in the sclerotic group were significantly lower than those in the normal group(P<0.01).There were significant differences in obesity,muscle mass and combined classification between the two groups(P<0.01).Logistic regression analysis showed that obesity and muscle mass decline were both risk factors for atherosclerosis(P<0.05),but muscle mass was no longer risk factor for atherosclerosis in the combined classification(P>0.05).Conclusions:The middle-aged and elderly people can monitor the occurrence of arteriosclerosis and its dynamic changes in the intervention by combining body composition indicators,especially those with obesity,muscle mass decline and obesity combined with muscle mass decline should pay more attention to the screening and prevention of arteriosclerosis.