摘要
Mitochondria energize the inner ear to maintain the cochlear potential createdbythe striavascularis,assist the motility of outer hair cells,perform synaptic processes,and maintain the spontaneous and sound-driven discharges of the spiral ganglion neurons(SGNs).Mitophagy deficiencies induce the accumulation of damaged organelles and mitochondria in cells and are a primary cause of drug-induced hearing loss.
基金
supported by grants from the National Natural Science Foundation of China(No.82171158,82271177,82271185,82171155)
the National Key Research and Development,Project of China(No.2020YFC2008500).
