摘要
The kidney,a central regulator of systemic homeostasis essential for human health,plays a vital role in various metabolic pathways,including fatty acid metabolism,gluconeogenesis,glycolysis,and mitochondrial metabolism.Chronic kidney disease(CKD)manifests as a progressive decline in renal function,marked by reduced glomerular filtration rate(GFR)or persistent kidney damage persisting for more than three months.
基金
supported by the National Natural Science Foundation of China(82003102,82300787,82170598)
Hunan Provincial Key Field R&D Plan Project(2022SK2034)
Natural Science Foundation of Hunan Province(2022JJ30058,2021JJ40992)
the Youth Science Foundation of Xiangya Hospital(2021Q11)。
