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肌少症与代谢综合征相关疾病的研究进展

Research progress of sarcopenia and metabolic syndrome-related diseases
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摘要 肌少症(sarcopenia)是一种与增龄相关的全身性骨骼肌疾病,主要表现为骨骼肌质量和功能的丧失。肌少症发病率逐年上升,其病因复杂并相互影响,发病机制尚未完全明确,有研究发现其与代谢综合征(MS)密切相关。骨骼肌是胰岛素诱导葡萄糖代谢的主要器官,肌肉量的损失与肌少症和MS紧密关联,两者都与增龄、代谢能力有关,均为年龄相关性疾病。MS是以高血压、糖尿病、肥胖和高尿酸血症为主,多种代谢性疾病共存的临床症候群。本文就肌少症与MS相关疾病的研究进展做一综述。 Sarcopenia is an age-related systemic skeletal muscle disease characterized by loss of skeletal muscle mass and function.The incidence of sarcopenia is increasing year by year.The causes of the disease are complex and interacts with each other.The pathogenesis is not completely clear.Studies have found that sarcopenia is closely related to metabolic syndrome(MS).Skeletal muscle is the main organ of insulin-induced glucose metabolism.The loss of muscle mass is closely related to sarcopenia and MS.Both of them are related to aging and metabolic capacity,and are age-related diseases.MS is a clinical syndrome characterized by hypertension,diabetes,obesity,and hyperuricemia,and a variety of metabolic diseases coexist.This article reviews the research progress of sarcopenia and metabolic syndrome-related diseases.
作者 罗莎莎 练凤江 谢艳 翟朋 杨帆 LUO Sha-sha;LIAN Feng-jiang;XIE Yan;ZHAI Peng;YANG Fan(Department of Geriatrics,the Third Affiliated Hospital of Zunyi Medical University/the First People's Hospital of Zunyi,Zunyi 563000,Guizhou,CHINA)
出处 《海南医学》 CAS 2024年第17期2572-2575,共4页 Hainan Medical Journal
关键词 老年人 肌少症 代谢综合征 相关性 Elderly Sarcopenia Metabolic syndrome Correlation
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