化痰清肺方联合西医基础疗法治疗痰热蕴肺型卒中相关性肺炎疗效观察

Efficacy of Huatan Qingfei Prescription combined with basic Western medical therapy in treatment of phlegm-heat and lung stroke-related pneumonia

目的观察化痰清肺方联合西医基础疗法治疗痰热蕴肺型卒中相关性肺炎(SRP)的疗效。方法将我院60例痰热蕴肺型SRP患者随机分为对照组与治疗组各30例。对照组采用西医基础疗法治疗,治疗组采用化痰清肺方联合西医基础疗法治疗。比较肺炎疗效,记录体温恢复、白细胞恢复、病灶完全吸收时间,比较临床肺部感染(CRIS)评分、中医证候积分,检测体温(T)、白细胞计数(WBC)、中性粒细胞比值(N%)、C反应蛋白(CRP),记录病原菌清除率。结果治疗后,治疗组肺炎总有效率高于对照组(P<0.05);治疗组体温恢复、白细胞恢复、病灶完全吸收均短于对照组(P<0.05);两组CRIS评分、中医证候积分均低于治疗前,治疗组CRIS评分、中医证候积分均低于对照组(P<0.05);两组T、CRP、WBC、N%均低于治疗前,治疗组T、CRP、WBC、N%均低于对照组(P<0.05);治疗组病原菌清除率高于对照组(P<0.05)。结论化痰清肺方联合西医基础疗法明显提高治疗痰热蕴肺型SRP的疗效,促进病情康复,减轻肺部感染,控制中医证候,抑制炎症因子,提高病原菌清除率。

Objective To observe the efficacy of Huatan Qingfei Prescription combined with basic Western medical therapy in treatment of phlegm heat and lung stroke-associated pneumonia(SRP).Methods A total of 60 patients with sputumheat-lung SRP were randomly divided into control group and treatment group with 30 cases each.Control group was treated with basic Western medical therapy,and treatment group was treated with Huatan Qingfei Prescription on the basis of control group.The efficacy of pneumonia,the time of body temperature recovery,leukocyte recovery,and complete absorption of lesions,the scores of clinical pulmonary infection(CRIS)and TCM syndrome,body temperature(T),white blood cell count(WBC),neutrophil ratio(N%),and C-reactive protein(CRP),and pathogen clearance in the two groups were compared.Results After treatment,the total effective rate of pneumonia in treatment group was better than that in control group(P<0.05);the body temperature,leukocyte recovery,and complete absorption of lesions in treatment group were lower than those in control group(P<0.05);the CRIS score and TCM pattern score of both groups were lower than those before treatment,and were lower in treatment group than those in control group(P<0.05);the T,CRP,WBC,and N%in both groups were lower than those before treatment,and were lower in treatment group than those in control group(P<0.05);the pathogen clearance rate of treatment group was higher than that of control group(P<0.05).Conclusion Huatan Qingfei Prescription combined with basic Western medical therapy can significantly improve the efficacy of phlegm-heat-accumulation pulmonary SRP,promote recovery,alleviate lung infection,control TCM syndromes,inhibit inflammatory factors,and improve the clearance rate of pathogenic bacteria.