冠状病毒组装及释放机制的研究进展

Research progress on the assembly and release mechanisms of coronaviruses

冠状病毒在近几十年中引起了多次大规模的传染病造成了严重的人员伤亡,严重威胁着人类的生命健康。病毒的组装与释放是冠状病毒生命周期的关键阶段,因此对冠状病毒组装和释放机制进行研究是至关重要的。该文对冠状病毒组装包装机制、冠状病毒多种释放途径以及相应的靶向抗病毒药物进行阐述,为其应对冠状病毒的预防与治疗提供参考。

In recent decades,the advent of coronaviruses has engendered multiple large-scale infectious outbreaks,leading to profound human casualties and posing a significant menace to global public health.At the crux of the coronavirus lifecycle,the assembly and release phases emerge as pivotal processes,necessitating meticulous investigation into the underlying mechanisms.This paper systematically expounds upon the intricate assembly and packaging mechanisms intrinsic to coronaviruses,scrutinizes the diverse release pathways employed by these viruses,and delves into the discourse surrounding targeted antiviral drugs.The comprehensive insights encapsulated in this exposition serve as valuable reference points for formulating effective strategies in the prevention and treatment of coronavirus infections.