老年抑郁症患者抑郁评分与认知能力的关系

Relationship Between Depression Score and Cognitive Ability in Elderly Patients with Depression

评估老年抑郁症患者抑郁症状得分与其认知能力,阐述老年抑郁症状的严重性与认知功能的相互影响,深入探讨二者间的关系,选取76例老年抑郁症患者为研究对象,采用问卷调查法和老年抑郁量表(GDS)、简易智力测试量表(MMSE)评估老年抑郁症患者的抑郁评分、认知功能水平,探究其相关性。评估结果显示,女性、年龄>70岁及小学以下文化程度的患者认知能力受损更明显(P<0.05);治疗1个月后老年抑郁症患者的抑郁评分显著低于治疗前(P<0.05),老年抑郁症患者在定向力、注意计算力、记忆力、回忆、语言能力及总得分显著高于治疗前(P<0.05);Pearson相关系数比较结果证明老年抑郁症患者的抑郁评分与认知功能单项指标之间呈负相关,说明老年抑郁症患者的病情严重程度与其认知功能损害之间存在密切联系。随着抑郁症状的缓解,其认知功能可得到显著改善。

The study evaluates the depressive symptom score and cognitive ability of elderly patients with depression,elaborates the interaction between the severity of depressive symptoms and cognitive function,deeply explores the relationship between the two,selects 76 elderly patients with depression as research objects,evaluates the depression score and cognitive function level of elderly patients with depression with Questionnaire survey,Geriatric Depression Scale(GDS)and Simple Intelligence Test Scale(MMSE),and explores their correlation.Evaluation results show that the impairment of cognitive ability is more obvious in female patients,age>70 years old and patients with education below primary school(P<0.05).The depression scores of elderly patients with depression after 1 month of treatment is significantly lower than those before treatment(P<0.05).Orientation,attention computing,memory,recall,language ability and total score of elderly patients with depression are significantly higher than those before treatment(P<0.05).The results of Pearson correlation coefficient comparison show that depression score in elderly patients with depression is negatively correlated with a single index of cognitive function,indicating that there is a close relationship between the severity of illness and cognitive function impairment in elderly patients with depression.With the remission of depressive symptoms,cognitive function can be significantly improved.