食用菌多糖调控肠道微生态的研究进展

Research Progress on the Regulating of Intestinal Microecosystem by Edible Mushroom Polysaccharides

肠道内的微生物菌群及所处的环境构成了一个微生态系统,这个微生态系统在很多方面对生物体产生影响,很多疾病的发生也与肠道微生态失衡有着或多或少的关系。食用菌多糖是一类重要的生物活性物质,大量研究表明其具有极高的药用价值,近年来,研究者发现食用菌多糖通过调控肠道微生态改善肠道功能,在各种代谢疾病及全身炎症的治疗中,展现出巨大的应用潜力。本文综述了食用菌多糖对肠道微生态的调控机制及其对肥胖、糖尿病、炎症性肠炎等多种疾病的功效,对食用菌多糖的临床药物开发及代谢疾病治疗应用具有一定参考价值。

The intestinal microflora in the gut and the environment they live in constitute a microecological system,which affects organisms in many aspects.The occurrence of many diseases is also more or less related to the imbalance of intestinal microecosystem.Edible mushroom polysaccharide are an important class of bioactive substances,and has been shown in many studies that it has extremely high medicinal value.In recent years,researchers have found that edible mushroom polysaccharides improve intestinal function by regulating intestinal microecology,and have showed great application potential in the treatment of various metabolic diseases and systemic inflammation.This paper reviewed the regulation mechanism of edible mushroom polysaccharides on intestinal microecology and its effect on obesity,diabetes,inflammatory enteritis,and other diseases,which has certain reference value for clinical drug development and the application of dible mushroom polysaccharides in the treatment of metabolic disease.