摘要
[目的]探讨石菖蒲、冰片对缺氧损伤神经细胞的保护作用。[方法]在缺氧培养条件下造成大鼠神经细胞损伤,测定空白对照组、模型对照组、石菖蒲挥发油组、冰片组、冰片+石菖蒲挥发油(低、中、高配比)组神经元细胞数、神经细胞支配面积。[结果]石菖蒲挥发油、冰片、冰片+挥发油(低、中、高配比)给药组神经细胞支配面积和神经元细胞数高于空白对照组和模型对照组。[结论]石菖蒲、冰片对缺氧诱导的大鼠神经细胞损伤具有保护作用。
[Objective] To explore the protective effect of Borneol and volatile oil of Rhizoma Acori Tatarinowii (RAT) on anoxic damage of nerve cells (NC). [Methods] NC damage in rats were induced by anoxic culture solution. The number of NC and the domination area of NC in normal control group (Group A), model control group (Group B) , RAT volatile oil group (Group C), borneol group (Group D), borneol (20 g/L) and RAT volatile oil (7.3 g/L, 11 g/L and 14.6 g/L) groups (Group E, Group F and Group G) were measured. [Results] The number of NC and the domination area of NC in Group C, Group D, Group E, Group F and Group G were larger than those in Group A and Group B. [Conclusion] Borneol and volatile oil of RAT exert a protective effect on anoxic damage of NC.
出处
《广州中医药大学学报》
CAS
2003年第1期63-65,共3页
Journal of Guangzhou University of Traditional Chinese Medicine
关键词
脑损伤
中药疗法
神经元
药物作用
石菖蒲
冰片
药理学
CEREBRAL DAMAGE/TCD therapy
NEURONS/drug effects
ACORUS TATARINOWII /phannacology
BORNEOLUM SYNTHETICUM/phaimacology
