854例甲状腺癌患者临床特征分析

Analysis of clinical characteristics of 854 patients with thyroid cancer

目的:总结分析甲状腺癌手术患者的临床特征,为临床诊疗提供信息和指导。方法:收集2013—2018年854例甲状腺癌手术患者的临床资料,按年龄段分组,对其年龄、性别、病理学类型、颈部淋巴结转移等进行分层研究。结果:2013—2018年甲状腺癌手术患者总例数呈增长趋势。不同年份甲状腺癌手术患者年龄构成差异无统计学意义(P>0.05),但20~54岁患者随着年龄增长发病人数有逐渐增加的趋势,50~54岁达高峰,随后逐渐下降。2013—2018年甲状腺癌手术患者的性别构成差异无统计学意义(P>0.05),但在40~44岁、50~54岁年龄区间女性患病率高于男性(P<0.05),70~74岁年龄区间男性患病率高于女性(P<0.05),二者的高峰期均在50~54岁。2013—2018年甲状腺癌手术患者病理类型中乳头状癌占比较高(占96.8%),在40~44岁年龄区间女性发病率高于男性(P<0.01),在70~74岁年龄区间男性发病率高于女性(P<0.01)。滤泡状癌(占1%)男性发病率高于女性(P <0.05)。女性甲状腺癌患者淋巴结转移发生率低于男性(P<0.05)。结论:不同年龄段甲状腺癌患者发病各有特征,应分年龄段制定防控措施。

Objective:The aim of this study is to summarize and analyze the clinical features of thyroid cancer surgery patients,and provide information and guidance for clinical diagnosis and treatment.Method:The medical records of 854 patients with thyroid cancer who met the inclusion criteria from January 2013 to December 2018 were collected from the hospital’s medical record system.Patients were grouped by age group and their stratified studies were performed on age,gender,pathological type,and cervical lymph node metastasis.Result:The total number of patients with thyroid cancer surgery in 2013-2018 showed an increasing trend.There was no significant difference in the age composition of thyroid cancer patients between different years(P>0.05),but the age of20-54 years old gradually increased with age,and reached a peak at 50-54 years old,then gradually decreased.There was no significant difference in gender composition between patients with thyroid cancer surgery in 2013-2018(P>0.05),but in 40-44 years old,the prevalence of women in the 50-54 age group was higher than that in men(P<0.05),The prevalence of men in the 70-74 age group was higher than that in women(P<0.05),and the peak period of both was 50-54 years old.Papillary carcinoma accounted for a high proportion(96.8%)in the pathological types of thyroid cancer surgery patients in 2013-2018,and the incidence of women in the 40-44 age group was higher than that in men(P<0.01),in the 70-74 age range.The incidence was higher than that of women(P<0.01).The incidence of follicular carcinoma(1%)was higher in men than in women(P<0.05).The incidence of lymph node metastasis in women with thyroid cancer was lower than that in men(P<0.05).Conclusion:The incidence of thyroid cancer in different age groups has its own characteristics,and prevention and control measures should be formulated according to age groups.