早期颅骨缺损修补术对病人神经功能修复的改善作用

Effect of early cranial defect repair on nerve function repair in patients

目的探讨早期颅骨缺损修补术对病人神经功能修复的改善作用。方法颅骨缺损病人60例,随机分为对照组和观察组,每组各30例,对照组采用传统时间颅骨缺损修补术(术后3～6个月),观察组采用早期颅骨缺损修补术(术后1～3个月),比较两组病人术后疗效、日常生活能力(ADL)评分、Fugl-Meyer评分及神经功能缺损评分、生活质量评分。结果采用早期颅骨缺损修补术的病人的优良率93. 33%,显著高于对照组的66. 67%(P <0. 05);采用早期颅骨缺损修补术的观察组病人的术后ADL评分、Fugl-Meyer评分均显著高于对照组(P <0. 05);且观察组病人的神经功能缺损评分显著低于对照组(P <0. 05);观察组病人的SF-36量表除躯体疼痛维度评分均显著高于对照组(P <0. 05)。结论早期颅骨缺损修补术能够帮助颅骨缺损病人提高临床疗效,并提高病人日常生活能力、生活质量、运动功能及减少病人躯体疼痛及术后神经功能缺损程度,临床效果显著。

Objective To investigate the effect of early cranial defect repair on nerve function of patients. Methods 60 patients with cranial defect admitted to our hospital were selected. They were randomly divided into control group( n = 30) and observation group( n = 30). The control group was treated with traditional cranial defect repair( 3 ~ 6 months after operation) and the observation group with early cranial defect repair( 1 ~ 3 months after operation). The ADL score,Fugl-Meyer score and quality of life score were compared between the two groups. Results The excellent and good rate of the patients with early cranial defect repair was 93. 33%,which was significantly higher than that of the control group( 66. 67%,P < 0. 05). Tthe ADL score and Fugl-Meyer score of the observation group with early cranial defect repair was significantly higher than that of the control group( P < 0. 05). The scores of neurological impairment of the observation group were significantly lower than those in the control group( P < 0. 05),and the scores of the SF-36 scale in the observation group were significantly higher than those in the control group( P < 0. 05). Conclusion Early cranial defect repair can help patients with skull defect to improve the clinical efficacy,improve the ability of daily life,quality of life,motor function and reduce the somatic pain and the degree of postoperative neurological deficit. The clinical effect is remarkable.