摘要
本文分析鼻咽癌开始放疗后出现远处转移77例,探讨其转移的有关因素、临床特点、转移灶的治疗以及预后问题。分析结果表明:放疗剂量及放疗位置与远处转移无关。病理类型、临床分期与转移有关。癌细胞分化程度差和晚期病例易发生转移。远处转移的常见部位是骨、肝、肺,骨转移又以盆骨、脊椎骨为多见。在发生远处转移的病例中,颈结转移的影响显著大于鼻咽原发灶;放疗前全身化疗防止远处转移的效果不肯定。对局部单纯骨转移灶放疗效果较好,能消除症状、提高局控,部分延长生存期。
In order to determine the related factors of metastases, clinical features, treatment for the meta-stastic foci and prognosis, 77 patients with nasopharyngeal carcinoma (NPC) occurring distant metastases after the beginning of radiotherapy were analyzed. The results of the present series dem-onstrated that the dosage and the recetpive spot of radiation was not correlative, and histopathological type and clinical stage, especially N stage were factors concerned. The frequency of organs and tissues involved was in turn as foll ows:bone, liver and lungs. Pelvis and vertebral column were most often involved in the skeleton. The effect of induction chemoth erapy to prevent distant metasta-ses was still uncertain, and radiotherapy was effective in patients with only bone metastasis.
出处
《海南医学》
CAS
1992年第3期52-54,共3页
Hainan Medical Journal
关键词
鼻咽肿瘤
放射疗法
转移
Nasopharyngeal carcinoma(NPC) Metastases Radiotherapy