摘要
利用β—环糊精分别对蟾酥醇溶性成分和冰片进行了包合,较全面地考察了影响包合效果的诸多因素,分别确定研磨法和饱和水溶液法为蟾酥β—CD 包合物和冰片β—CD 包合物的制备方法。按最佳工艺制备的两种包合物含量适中,重量收率和包结率均较原有报道有所提高;且经差示热分析法和粉末X 射线法鉴定,证明上述两种包合物确已形成。
Inclusion complexes of
Chansu and Borneol with β-cyclodexrin
were experimentally prepared,by using
grinding and coprecipitation method,re-
spectively.Evidences that these products
are ture inclusion complexes and not si-
mple phsical mixtures were substantiated
based on differential thermal analyses
(DTA)and powder X-ray diffractometry.
出处
《华西药学杂志》
CAS
CSCD
北大核心
1992年第3期138-142,共5页
West China Journal of Pharmaceutical Sciences
关键词
蟾酥
冰片
包合物
Β环糊精
Chansu
Borneol
β-cyclodextrin
Inclusion complex