p73基因与乳腺癌
摘要
p73基因作为p5 3基因家族新发现的成员之一 ,其编码蛋白在结构和功能上与p5 3蛋白很相似 ,但也存在显著的差异。p73基因在乳腺癌的发生。
出处
《国外医学（生理病理科学与临床分册）》
2003年第4期374-376,共3页
Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
参考文献20
-
1Kaghad M, Bonnet H, Yang A, et al. Monoallelically expressed gene related to p53 at 1 p36, a region frequently deleted in neuroblastoma and other human cancers [J]. Cell, 1997, 90(4) :809-819.
-
2Shishikura T, Ichimiya S, Ozaki T, et al. Mutational analysis of the p73 gene in human breast cancers[J]. Int J Cancer, 1999, 84(3) :321-325.
-
3Ichimiya S, Nimura Y, Kageyama H, et al. p73 at chromosome 1 p36.3 is lost in advanced stage neuroblastoma but its mutation is infrequent[J]. Oncogene, 1999, 18(4): 1061-1066.
-
4Takada N, Ozaki T, Ichimiya S, et al. Identification of a transactiration activity in the COOH-Terminal region of p73 which is impaired in the naturally occurring mutants found in human neuroblastomas[J]. Cancer Res, 1999, 59(12) :2810-2814.
-
5Wang WK, Proctor MR, Buckle AM, et al. Crystallization and preliminary crystallographic studies of SAM domain at the c-terminus of human p73 alpha[J]. Aeta Crystallogr D Biol Crystallor, 2000, 56(pt6) :769-771.
-
6Zaika AI, Kovalev S, Marchenko ND, et al. Overexpression of the wild type p73 gene in breast cancer tissues and cell lines [ J ].Cancer Res, 1999, 59(13) :3257-3263.
-
7lshimoto O, Kawahara C, Enjo K, et al. Possible oneogenie potential of ANp73 : a newly identified isoform of human p73[ J]. Cancer Res, 2002, 62(3) :636-641.
-
8Stiewe T, Zinunermann S, Frilling A, et al. Transactivation-deficient △TA-p73 acts as an oncogene [ J ]. Cancer Res, 2002,62( 13 ) :3598-3602.
-
9Yang A, Walker N, Bronson R, et al. p73-deflcient mice have neurological, pheromonal and inflammatory defects but lack spontaneous minors[J]. Nature, 2000, 404(6773) :99-103.
-
10Tokuchi Y, Hashimoto T, Kobayashi Y, et al. The expression of p73 is increased in lung cancer, independent of p53 gene alteration[J]. Br J Cancer, 1999, 80(10) :1623-1629.
-
1龚丹,钟荣梅,朱水山.p73基因的研究进展[J].南昌大学学报（医学版）,2011,51(1):83-85. 被引量：2
-
2张增锋,马敏怡.p73基因与肿瘤关系的研究进展[J].中国医学文摘（肿瘤学）,2001,15(3):258-260.
-
3黄君富,房殿春,鲁容.p73基因[J].生命的化学,1998,18(3):7-8.
-
4田辉,王善政,彭书华.p73基因蛋白表达与肺癌临床病理学特征及预后关系的探讨[J].中国肿瘤生物治疗杂志,2004,11(2):128-128.
-
5赵中海,朱立新,耿小平.p73基因研究进展[J].医学分子生物学杂志,2004,1(1):58-62. 被引量：2
-
6钟婷,魏招秀,况海斌.p53基因家族与生殖功能的研究进展[J].南昌大学学报（医学版）,2012,52(10):86-89.
-
7周宏众,韩少良.p73基因生物学功能及其在胃癌组织表达的临床意义[J].中华普通外科学文献（电子版）,2008,2(4):56-58.
-
8梁伟,夏海龙,李静,赵春华.干扰p73基因对脂肪间充质干细胞向神经细胞分化的影响[J].安徽医科大学学报,2011,46(12):1260-1263.
-
9胡晓鹃,张吉翔.p73基因与细胞凋亡[J].国外医学（遗传学分册）,2003,26(5):257-260. 被引量：5
-
10朱栋元,马廷行.p73基因研究进展[J].肿瘤防治杂志,2005,12(24):1909-1912. 被引量：2
