复元活血汤抗炎镇痛作用的实验研究

AN EXPERIMENTSL STUDY ON THE EFFECT OF "FUYUAN HUOXUE TANG" ON ANTI-INFLAMMATION AND ANALGESIA

为研究复元活血汤的抗炎、镇痛作用 ,进行了药效学研究。结果显示 ,复元活血汤对醋酸引起的小鼠腹腔毛细血管通透性增加、角叉菜胶所致的大鼠足跖肿胀、二甲苯所致的小鼠耳肿胀均有显著的抑制作用 ;能显著降低小鼠腹腔注射醋酸引起的扭体反应次数 ,明显提高小鼠热板法的痛阈值 ,说明该药有较强的抗炎、镇痛作用。

The anti-inflammatory and analgesic effect of 'FUYUAN HUOXUE TANG''(FHT, a TCD decoction for restoring the vital energy and activating the blood circulation) was explored through pharmacodynamics studies. The results showed that FHT could significantly inhibit the acetic-acid-induced increase of mouse abdominal capillary permeability, carrageenin-induced rat planta edema and xylol-induced mouse ear edema, reduce the times of acetic-acid-induced mouse body twisting and improve the pain threshold of mouse hot plate method, suggesting that the drug has a strong anti-inflammatory and analgesic effect.