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脂蛋白a水平与冠脉病变的相关性研究 被引量:5

Correlation between plasma lipids and coronary artery disease
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摘要 目的:通过对冠心病患者的血脂水平进行监测,阐明各种血脂指标对冠心病危险因素的预测价值。方法:行冠状动脉造影术的患者,其中冠心病79例,男39例,女40例,对照组61例,男26例,女35例,测定其总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)及脂蛋白 a(Lpa)水平。结果:冠心病患者TC、TG、LDL和HDL水平与对照组无明显差异,Lpa水平较对照组明显升高(P<0.05),Lpa水平与冠状动脉狭窄程度呈正相关(r=0.90,P<0.01)。结论:Lpa与冠状动脉粥样硬化范围及程度相关。 Objective:To evaluate the correlation of the plasma lipids to the extent,serverity of coronary artery diseases. Methods: In 140 patients undering coronary angiography, plasma lipids were measured with usual procedures. Results: There was a positive association between Lpa and the extent and severity of coronary artery disease, there was no difference in plasma lipids between coronary artery disease goroup and controls. Conclusions: Elevated Lpa correlated well with the extent,severity of the coronary artery disease.
出处 《国外医学(心血管疾病分册)》 2003年第6期378-379,共2页
关键词 脂蛋白A 冠脉病变 相关性研究 冠心病 血脂 Coronary artery diseases Plasma lipids Lpa
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参考文献8

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二级参考文献3

  • 1Kitchin AH, Milne JS. Longitudinal survey of ischaemic heart disease in a randomly selected sample of older population. Br Heart J, 1997,39∶889-893.
  • 2Rhoads GG, Dahlen G, Berg K, et al. Lp(a) lipoprotein as a risk factor for myocardial infarction.JAMA, 1986, 2566∶2540.
  • 3吴春芳,陈良华,陆国平,龚兰生.脂蛋白(a)对HepG_2细胞纤溶酶原激活物抑制物-1分泌的影响[J].中华心血管病杂志,1999,27(3):231-233. 被引量:35

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