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MicroRNA在阿尔茨海默病中的作用及机制 被引量：1

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摘要 微RNA(miRNA)是真核生物中广泛存在的非编码RNA,长约21到23个核苷酸,预测转录后调节至少一半的人类转录组〔1〕。近年来发现,miRNA可能在阿尔茨海默病(AD)等神经退行性疾病的发生发展中发挥重要的调控作用。了解和探讨miRNA在AD中的作用及其机制可为临床寻找特异性的治疗靶点提供基础。1 miRNA的生物学基础miRNA的生物合成途径是高度保守的。
作者 田金鑫 邵水金 国海东
机构地区 上海中医药大学基础医学院解剖教研室
出处 《中国老年学杂志》 CAS CSCD 北大核心 2015年第21期6271-6274,共4页 Chinese Journal of Gerontology
基金 国家自然科学基金资助课题(81102670 31400838 81373754)
关键词 阿尔茨海默病 微RNA Β淀粉样蛋白
分类号 R749.16 [医药卫生—神经病学与精神病学]
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参考文献10

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共引文献2

同被引文献23

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中国老年学杂志
2015年 第21期

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