针刺联合芍药汤加减治疗溃疡性结肠炎

Acupuncture Combined with Peony Decoction in the Treatment of Ulcerative Colitis

目的探讨针刺联合芍药汤加减治疗溃疡性结肠炎临床疗效。方法选取2014年3月-2016年10月我院收治的120例活动期溃疡性结肠炎患者作为研究对象,按照简单随机法将患者分为3组,各40例,分别行针灸治疗、中药治疗及针灸联合中药治疗。比较3组临床症状及体征评分、肠镜观察及病理组织的改变情况及临床疗效。结果联合组治疗总有效率为95.00%,明显优于针灸组的67.50%及中药组72.50%(P <0.05);3组患者治疗后腹痛、腹泻、里急后重、脓血及肛门灼热评分均低于治疗前(P <0.05),联合组优于针灸组及中药组(P <0.05);3组患者治疗后肠镜及病理组织评分均低于治疗前(P <0.05),联合组优于针灸组及中药组(P <0.05)。结论针刺联合芍药汤加减方可以抑制机体免疫反应,保护肠黏膜,改善肠道运动功能,调气血、化瘀滞,进而改善患者临床症状,提高治疗效果。

Objective Study on the clinical effect of acupuncture combined with peony decoction in the treatment ofactiveulcerative colitis. Methods 120 patients with active ulcerative colitis admitted in our hospital from March2014 to October 2016 were selected as study subjects and randomly divided into three groups, 40 cases each. Each group was treated with acupuncture and moxibustion, traditional Chinese medicine and acupuncture combined with traditional Chinese medicine. Comparison of therapeutic effect, clinical symptoms and signs score, endoscopic observation and pathological changes. Results The total effective rate of the combined group was 95.00%, which was significantly better than that of the acupuncture group(67.50%) and the traditional Chinese medicine group(72.50%)(P < 0.05). The scores ofabdominal pain, diarrhea, tenesmus, passing stool with pus and blood and burning pain were lower in three group than before treatment(P < 0.05), the combined group is superior to the acupuncture group and the traditional Chinese medicine group(P < 0.05). The scores of endoscopic and histopathology in the three groups were lower than those before treatment(P < 0.05), the combined group is superior to the acupuncture group and the traditional Chinese medicine group(P < 0.05). Conclusion Acupuncture combined with peony decoction can inhibit the body immune response, protect the intestinal mucosa, improve the intestinal motility, regulate qi and blood,remove stagnation of blood stasis, and improve the clinical symptoms of patients and the therapeutic effect.