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4-(3,4-二氯苯基)-1-萘满酮合成述评 被引量:2

Summary on the Synthesis Method of 4-(3,4-dichlorophenyl)-1-tetralone
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摘要 综述了4-(3,4-二氯苯基)-1-萘满酮的应用及合成方法,对不同路径的原料、催化剂及产率进行了介绍,并对这几种合成路径进行了比较。结果表明采用1-萘酚和邻二氯苯为原料,无水AlCl3作催化剂是一条理想和合成路线。 Application and synthesis methods of 4-(3,4-dichlorophenyl)-1-tetralone are summarized in this short paper, involving the materials, catalysts and yield. Different preparative routes are also compared.
出处 《江苏化工》 2003年第5期27-29,共3页 Jiangsu Chemical Industry
关键词 4-(3 4-二氯苯基)-1-萘满酮 合成 抗抑郁剂 中间体 盐酸舍曲林 4-(3,4-dichlorophenyl)-1-tetralone antidepressant intermediate sertraline hydrochloride review
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  • 1Quallich, George J. Process for preparing sertraline from chiral tetraline[ P] .EP:1059 287 A1.2000-05-06.
  • 2Willard Jr. Antidepresant derivatives of cis - 4 - phenyl - 1,2,3,4- tetrahydro lnaphthalenamine[ P]. US:4 536 518.1985 - 08 - 20.
  • 3George J,Quillich. Fredel- crafts synthesis of 4- (3,4- dichlorophenyl) - 3,4 - dihydo - 1 (2H)-naphthalenone, a key intermediate in the preparation of the antidepressant sertraline[J]. Journal of Organic Chemistry, 1990,55:4 971-4 973.
  • 4Quallich. Process for preparing a 4,4- diphenylbutanoic acid derivative[P]. US:4 777 288. 1988- 10- 11.
  • 5Quallich. Process for prepping sertraline intermediates[ P].US:4 839 104.1989 - 06 - 13.
  • 6Adrian G P. Method of Preparing 4 - dichlorophenyl - 1 - tetralones[P]. US:5 019 655. 1991 -05-28.
  • 7Lauten M, Rovis T. General strategy toward the tetrahydronaphthalene skeleton, an expedient total synthesis of semaline[J]. Journal of Organic Ghemistry, 1997,62:5 246-5247.
  • 8Lauten M, Rovis T. Selective functionalization 1,2- dihydronaphthalenonls leads to a concise, stereoselective synthesis of settraline[Ele]. Tetrahedron, 1999,55:8 967-8 976.

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