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p38MAPK与内皮细胞损伤的关系

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摘要 p3 8MAPK通过磷酸化转录因子引起多种相关基因转录 ,调控活性物质的表达 ,参与血管内皮细胞氧化应激损伤甚至凋亡等过程。在信号通路水平阻断和调控p3 8MAPK的表达和活性 ,可以达到控制和减轻内皮细胞损伤或凋亡的目的。
出处 《国外医学(生理病理科学与临床分册)》 2004年第1期31-33,共3页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
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