1[1]Iredale JP.Tissue inhibitors of metalloproteinases in liver fibrosis.Int J Biochem Cell Biol,1997,29:43～54.
2[2]Knittel T,Mehde M,Kobol D,et al .Expression patterns of matix metalloproteinases and their inhibitor in parenchymal and non-parenchymal cells of rat liver:regulation by TNF-α and TGF-β.J Hepatol,1999,30:48～60.
3[3]Iredale JP,Benyon RC,Pickering J,et al.Mechanisms of spontaneous resolution of rat liver fibrosis.hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors.J Clin Invest,1998,102:538～549.
4[4]Lee HS,Huang GT,Miau LH,et al.Expression of matrix metalloproteinases in spontaneous regression of liver fibrosis.J Hepatogastraenterology,2001,48(40):1114～1117.
5[5]Murawaki Y,Ikuta Y,Idobe Y,et al.Tissue inhibitor of metalloproteinase-1 in liver of patients with chronic liver disease.J Hepatol,1997,26(6):1213～1219.
6[6]Boeker KH,Haberkorn CI,Michels O,et al.Diagnostic potential of circulating TIMP-1 and MMP-2 as markers of liver fibrosis in patients with chronic hepatitis C.J Clin Chim Acta,2002,316(1-2):71～81.
7[7]Benyon RC,Iredale JP,Goddard S,et al.expression of tissue inhibitor of metalloproteinase-1 and -2 is increased in fibrotic human liver.J Gastroenterology,1996,110(3):821.
8[8]Takahara T,Furui K,Yata Y,et al.Dual expression of matric metalloprotein-2 and membranetype-1 matric metalloproteinase in fibrotic human liver.J Hepatol,1997,26(6):1521.
9[9]Lee HS,Huang GT,Cen CH,et al.Less reveral of liver fibrosis after prolonged carbon tetrachloride injection.J Hepatogastraente-rology,2001,48(41):1312～1315.
10[10]Iredale JP,Benyou RC,Pickering J,et al.Mechanisms of spontaneous resolution of rat liver fibrosis.Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors.J Clin Invest,1998,102:538～549.
2Li D, Friedman S L. Liver fibrogenesis and the role of hepatic stellate cell: new insights and prospects for therapy [J]. Gastroenterol Hepatol, 1999, 14(7): 618-633.
3Bedossa P, Houglum K, Trauwein C, et al. Stimulation of collagen Palha 1 (I) gene expression is associated withlipidpoerxldation in hepatocellular injury: a link to tissue fiborsis? [J]. Hepatology, 1994, 19(5): 1262-1271.
