摘要
目的 :探讨银杏叶片 (GinkgobilobaL .ExtractsTablets ,GbE)对2型糖尿病患者血脂 (TC、TG)水平及血液流变性的影响及其机理。方法 :82例 2型糖尿病患者随机分为对照组 ( 4 0例 ) ,口服达美康 ,每次 80mg,2次 /天 ;治疗组 ( 4 2例 ) ,在对照组用药的基础上加用银杏叶片口服 ,2片 /次 ,3次 /天 ;两组均连续用药一月。分别观察各组治疗前后FBG、TC、TG、FIB、动脉舒张压 (DBP)以及血液流变性指标的变化。结果 :治疗结束时治疗组TC、TG、FBG、FIB、ηb、ηp、EAI、TK、ESR、DBP等指标有显著性改善 (P <0 .0 5~ 0 .0 1) ;而对照组只有全血粘度高切值、ESR、TG、FBG、DBP等有改善 (P <0 .0 5 ) ,两组比较除FBG、DBP外 ,其他指标均有显著性差异 (P <0 .0 5~ 0 .0 1)。结论 :达美康加用银杏叶片治疗 2型糖尿病能改善血液流变性和微循环 ,预防血管性并发症 。
Objective: To investigate the effects of Ginkgo biloba Extracts(GbE) on total cholesterol(TC), triglycerides(TG) and hemorheology of patients with type2-diabets.Method: 82 cases of type2-diabets were randomized into group of control (n=40), treated with tablets of Diamicron; therapy group(n=42), treated with both tablets of GbE and Diamicron. Both two groups were treated for a month.Before and after the treatment the famine blood glucose(FBG)?TC?TG?fibrinogen(FIB)? diastole blood pressure (DBP) and hemorheological property were tested.Results: On the end of treatment TC?TG?FBG?FIB?ηb?ηp?EAI?TK?ESR and DBP of the therapy group are improved significantly (P<0.05~0.01); while there are only blood viscosity? ESR?TG?FBG?DBP improved in the control group (P<0.05). There are significant difference between the two groups except for FBG?DBP(P<0.05~0.01).Conclusion: Mentioned above Diamicron added the GBE to treat the type2-Diabets for improved the hemorheological property and microcisculation and to prevent the chronic complication,sach as the blood vessel complication is better than using the tablet of Diamicron only.
出处
《微循环学杂志》
2004年第2期16-17,共2页
Chinese Journal of Microcirculation
关键词
银杏叶片
达美康
2型糖尿病
血液流变学
血脂
胰岛素
Ginkgo biloba Extracts(GbE)
Type2-diabets
Hemorheology
Total cholesterol
Triglyceride