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代谢综合征痰瘀互结证量化诊断标准的研究

Study on Quantitative Diagnostic Criteria of Phlegm-stasis Interjunction Syndrome of Metabolic Syndrome
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摘要 目的确定代谢综合征痰瘀互结证量化诊断标准。方法基于文献研究制定《基于层次分析法的MS痰瘀互结证专家咨询问卷》,邀请专家填写问卷,采用专家群决策算法构建《MS痰瘀互结证诊断标准(草案)》。前瞻性收集MS患者,采用条件概率换算法、最大似然判别法对MS痰瘀互结证诊断标准进行临床验证并修订,制定MS痰瘀互结证量化诊断标准。结果建立的MS痰瘀互结证量化诊断标准诊断效能灵敏度95.7%,特异度84.0%,准确度91.6%,阳性似然比5.98,阴性似然比19.46。结论基于文献研究、专家咨询法及诊断性试验建立的MS痰瘀互结证量化诊断标准具有较好的诊断效能。 Objective To determine the quantitative diagnostic criteria of phlegm-stasis interjunction syndrome of metabolic syndrome.Methods Based on the literature research,the Expert Consultation Questionnaire for MS Syndrome of Phlegm-stasis Interjunction based on Analytic Hierarchy Process was developed.Experts were invited to fill out the questionnaire,and the Diagnostic Criteria for MS Syndrome of Phlegm-stasis Interjunction(Draft)was constructed by using the expert group decision algorithm.The patients with MS were prospectively collected,and the diagnostic criteria for phlegm-stasis interjunction syndrome of MS were validated and revised by conditional probability conversion method and maximum likelihood discrimination,and the quantitative diagnostic criteria for phlegm-stasis interjunction syndrome of MS were finally formulated.Results The sensitivity,specificity and accuracy of the established quantitative diagnostic criteria for MS phlegm-stasis interjunction syndrome were 95.7%,84.0%,91.6%,positive likelihood ratio 5.98,negative likelihood ratio 19.46.Conclusion The quantitative diagnostic criteria for MS phlegm-stasis interjunction syndrome established based on literature research,expert consultation and diagnostic tests have good diagnostic efficacy.
作者 刘亚丹 王斌 燕树勋 段飞 Liu Yadan;Wang Bin;Yan Shuxun;Duan Fei(First Affiliated Hospital,Henan University of Chinese Medicine,Zhengzhou 450000,China;First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300381,China;National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion,Tianjin 300381,China)
出处 《世界科学技术-中医药现代化》 CSCD 北大核心 2024年第1期242-251,共10页 Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金 河南省卫生健康委员会河南省第二批中医药拔尖人才培养项目(CZ0237-02):河南省中医药传承与创新人才培养项目,负责人:燕树勋 郑州市科学技术局郑州市科技惠民计划项目(2021KJHM0017):单纯性肥胖的中医综合诊疗方案推广与应用,负责人:燕树勋
关键词 代谢综合征 痰瘀互结证 量化诊断标准 层次分析法 Metabolic syndrome Phlegm-stasis interjunction syndrome Quantitative diagnostic criteria Analytic hierarchy process
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