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Analysis of heavy-ion-induced DNA strand breaks in plasmid pUC18

Analysis of heavy-ion-induced DNA strand breaks in plasmid pUC18
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摘要 Plasmid DNA was irradiated or implanted by mixed particle field(CR) or lithium-ion-beam to detect strand breaks.The primary results showed that mixed particle field could induce single and double strand breaks with positive linear-dose-effects;most of sequence changes induced by CR were point mutant.Lithium-ion-beam could induce strand breaks also,but it was only at dose of 20Gy. Plasmid DNA was irradiated or implanted by mixed particle field(CR) or lithium-ion-beam to detect strand breaks.The primary results showed that mixed particle field could induce single and double strand breaks with positive linear-dose-effects;most of sequence changes induced by CR were point mutant.Lithium-ion-beam could induce strand breaks also,but it was only at dose of 20Gy.
出处 《湖南农业大学学报(自然科学版)》 CAS CSCD 北大核心 2007年第S1期242-,共1页 Journal of Hunan Agricultural University(Natural Sciences)
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