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GnRH-R在大鼠递增负荷训练中的表达及与性激素的关系 被引量:4

Expression of GnRH R in Progressive Load Training for Rats and Its Relation with Sex Hormone
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摘要 :采用动物实验研究法 ,对促性腺素释放激素受体 (GnRH -R)在大鼠递增负荷训练中的表达及与性激素的关系进行分析。结果显示 ,长期大强度负荷使Ta组大鼠垂体GnRH -R表达明显低于C组 ,且同时伴有LH、E2 、P、T明显低于C组 ,FSH也低于C组 ;但是Ta组大鼠下丘脑、血浆 β -EP明显高于C组。休息 1周后GnRH -R未见恢复。认为 ,长期大强度负荷使Ta组大鼠垂体GnRH -R自身调节发生紊乱 ,是引起AMI的重要因素之一 ;过高的 β -EP抑制中枢GnRH分泌 ,是垂体GnRH -R表达减弱的主要抑制神经递质之一 ;推测AMI可能发生在下丘脑水平。 By animal experiments, the present paper analyzes the expression of GnRH-R in progressive load training for rats and its relation with sex hormone. The results show that the pituitary GnRH-R of Group Ta's rats under the long-term high intensity load is obviously lower than that of Group C's rats. Meanwhile, LH, E 2, P and T of Group Ta are significantly lower than that of Group Ta. Besides this, FSH of Group Ta is also lower than Group C. However, hypothalamus, and plasma β-EP of Group Ta are evidently higher than that of Group C. After a week's rest, there is no recovery in GnRH-R of Group Ta. It is obvious that the long term high intensity load brings about self-regulation disorder in pituitary GnRH-R of Group Ta's rats under the long-term high intensity load, which is one of the important factors in leading to AMI; overhigh β-EP would restrict the secretion of GnRH, which is one of the major factors in decreasing the expression of pituitary GnRH-R; it is inferred that AMI may occur in hypothalamus level.
出处 《上海体育学院学报》 CSSCI 北大核心 2001年第2期26-30,共5页 Journal of Shanghai University of Sport
基金 教育部博士点基金资助课题 第六届全国体育科学大会入选论文
关键词 促性腺素释放激素受体 大鼠 负荷训练 下丘脑 表达强度 性激素 GnRH-R rat load training hypothalamus expression intensity sex hormone
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  • 1[1]Loucks AB,et al. The reproductive system and exercise in women(J). Med Sci Sports Exe.1992,24(6):288~293
  • 2[2]Bebford TG, et al. Maximun oxyen consumuption of rats and its changes with various experimental procedures(J). Appl.physiol. 1979,47(6): 1278~1281
  • 3王人卫,胡贤豪,诸剑英,柯松儿,沙峰.女子举重运动员月经期不同负荷训练对经血量、血清睾酮、血红蛋白影响的研究[J].体育科学,1999,19(3):66-69. 被引量:13
  • 4王人卫,陆爱云,陈佩杰,郭仕达,蔡斌,高勇,段子才.递增负荷的运动性闭经动物模型的建立[J].中国运动医学杂志,2000,19(3):293-296. 被引量:20
  • 5[6]Kirkpatrick BL, et al. Estradiol and gonadotropin-releasing hormone(GnRH) interact to increase GnRH receptor expression in ovariectiomized ewes after hypothalamic-pituitary disconnection(J). Endocrine.1998,8(3):225~229
  • 6[7]Clarka IJ, et al. Neonatal immunization against gonadotropin-releasing hormone (GnRH) results in diminished GnRH secretion in adulthood(J). Endocrinology. 1998,139(4):2007~2021

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