心肌营养素-1及其信号转导

Cardiotrophin-1 and Its Signal Transduction

心肌营养素 1(Cardiotrophin 1,CT 1)是细胞因子IL 6家族成员,它能够诱导心肌细胞肥大,刺激心脏和神经细胞的存活,具有广泛的生物学作用.其生物活性通过多种信号转导途径实现.

As a member of the IL6 family of cytokines, Cardiotrophin1 (CT1) can induce hypertrophy of cardiac myocytes, stimulate the survival of both cardiac and neuronal cells, and has biologic pleiotropy, which were finished through several signal transductions.