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调磷因子:成纤维细胞生长因子23 被引量:11

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摘要 低磷性佝偻病/骨软化症的发生与体内的调磷因子有关。目前的研究表明成纤维细胞生长因子(FGF)-23属于体内重要的调磷因子,低磷性佝偻病/骨软化症患者的血循环中FGF-23水平升高。FGF-23可调节钠-磷共转运蛋白Ⅱa(NaPiⅡa)和1α羟化酶的活性从而引起低磷性佝偻病/骨软化症。
机构地区 中国医学科学院
出处 《国外医学(内分泌学分册)》 2004年第4期241-243,共3页 Foreign Medical Sciences(Section of Endocrinology)
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