摘要
目的:探讨肱动脉内-中膜厚度(IMT)与冠状动脉粥样硬化病变的关系。方法:接受冠脉造影检查的患者共149名。冠脉造影确诊为冠状动脉粥样硬化性心脏病的114名患者为冠心病组,冠脉造影正常除外冠心病的患者共35名为对照组。用高分辨率超声检测所有患者右侧肱动脉内径、IMT并计算半径与IMT的比值(R/IMT)并进行两组患者间的比较;分析影响肱动脉IMT的危险因素。结果:肱动脉IMT(r=0.301,P=0.000)和R/IMT(r=-0.268同,P=-0.001)与年龄增长显著相关;冠心病组患者肱动脉IMT有高于对照组的趋势(P=0.066);肱动脉内径及肱动脉IMT与冠脉病变严重程度相关(r分别为0.181和0.230,P=0.038和0.008);多元回归分析显示肱动脉IMT独立危险因素为年龄和空腹血糖。结论:肱动脉IMT与年龄呈正性直线相关,肱动脉IMT可能是冠状动脉粥样硬化的预测指标。
Objective: To investigate the relationship between intima-media thickness (IMT) of brachial artery and atherosclerosis of coronary artery. Methods: 149 patients were divided to coronary artery disease(CAD) group(n=114) and controll group(n=35) according to the results of coronary angiography. Mesured diameter and IMT of right brachial artery and calculate the ratio of radius and IMT (R/IMT), and compare these data between CAD group and controll group. Analyized the risk factors of IMT.Results: IMT(r=0.301, P=0.000) and R/IMT (r=-0.268, p=0.001) had significant relationship with age. There was a trend that IMT of CAD group was higher than that of controll group(P=0.066).The diameter and IMT related to the severity of coronary artery disease(r=0.181, P=0.038; and r=0.230,P=0.008, respectively). The independent risk factors of IMT were age and fasting blood glucose by multiple linear regression. Conclusion: IMT of brachial artery positively related to age and it would be a predictive maker of atherosclerosis of coronary artery.
出处
《中国医药导刊》
2004年第6期411-413,共3页
Chinese Journal of Medicinal Guide